Chance Energy-Linked Functions of Mitochondria

Papers Presented at the First Colloquium of the Johnson Research Foundation of the University of Pennsylvania, Philadelphia, April 13, 1963
1. Auflage 2013
ISBN: 978-1-4832-7167-5
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 294 Seiten, Web PDF

Energy-Linked Functions of Mitochondria presents the developments in the area of energy-linked functions of mitochondria. This book covers three general topics, namely, the generation, the transfer, and the utilization of reducing power. Organized into three parts encompassing 16 chapters, this book begins with an overview of the various steps involved in the combined electron and energy transfer reactions that lead to the generation of high-energy intermediates. This text then examines the effect of atracytloside and oligomycin on oxidative phosphorylation in submitochondrial particles. Other chapters consider a detailed review of the succinate-linked DPN reduction in submitochondrial particles. This book discusses as well the concept of energy-linked reversal of electron transport from reduced cytrochome c to pyridine nucleotide. The final chapter deals with the transient activation of respiration of tightly coupled mitochondria by adding low concentrations of calcium. This book is a valuable resource for scientists who are interested in energy-linked processes in mitochondria.

Autoren/Hrsg.

Chance, Britton

Inhaltsverzeichnis

1;Front Cover;1
2;Energy-Linked Functions of Mitochondria;4
3;Copyright Page;5
4;Table of Contents;10
5;Contributors;6
6;Preface;8
7;CHAPTER 1. INTRODUCTORY REMARKS;14
8;PART 1: THE GENERATION OF REDUCING POWER;16
8.1;CHAPTER 2. SOME ASPECTS OF OXIDATIVE PHOSPHORYLATION AND ITS REVERSAL IN SUBMITOCHONDRIAL PARTICLES;18
8.1.1;REFERENCES;29
8.2;DISCUSSION;30
8.3;CHAPTER 3. REDUCTIVE DEPHOSPHORYLATION OF ATP IN THE D...-C..NZYME Q SEGMENT OF THE RESPIRATORY CHAIN;39
8.3.1;REFERENCES;48
8.4;DISCUSSION;49
8.5;CHAPTER 4. THE ROLE OF PYRIDINE NUCLEOTIDE IN ENERGY LINKED REACTIONS;52
8.5.1;REFERENCES;61
8.6;DISCUSSION;62
8.7;CHAPTER 5. COUPLING OF ENERGY LINKED FUNCTIONS IN MITOCHONDRIA AND CHLOROPLASTS TO THE CONTROL OF MEMBRANE STRUCTURE;64
8.7.1;REFERENCES;84
8.8;DISCUSSION;85
8.9;CHAPTER 6. TOPOGRAPHY OF COUPLING FACTORS IN OXIDATIVE PHOSPHORYLATION;88
8.9.1;REFERENCES;94
8.10;DISCUSSION;95
8.11;CHAPTER 7. THE ENERGY-LINKED REDUCTION OF UBIQUINONE IN BEEF HEART MITOCHONDRIA;100
8.11.1;REFERENCES;103
8.12;DISCUSSION;105
9;PART 2: THE TRANSFER OF REDUCING POWER;108
9.1;CHAPTER 8. PROVISION OF REDUCING POWER FOR GLUTAMATE SYNTHESIS;110
9.1.1;REFERENCES;124
9.2;DISCUSSION;127
9.3;CHAPTER 9. MORPHOLOGICAL AND FUNCTIONAL ASPECTS OF PYRIDINE NUCLEOTIDE REACTIONS IN MITOCHONDRIA;134
9.3.1;SUMMARY;150
9.3.2;REFERENCES;151
9.4;DISCUSSION;153
9.5;CHAPTER 10. THE INTERACTION OF MITOCHONDRIAL PYRIDINE NUCLEOTIDES;156
9.5.1;Effect of Uncouplers;158
9.5.2;Effect of Phosphate on the Oxidation of Reduced Pyridine Nucleotides:;160
9.5.3;Reaction of Exogenous Pyridine Nucleotides;162
9.5.4;REFERENCES;165
9.6;DISCUSSION;166
9.7;CHAPTER 11. ENERGY-DEPENDENT REDUCTION OF TPN BY DPNH;170
9.7.1;REFERENCES;186
9.8;DISCUSSION;189
9.9;CHAPTER 12. SPECIFIC INHIBITORS OF ENERGY TRANSFER;194
9.9.1;REFERENCES ;212
9.10;DISCUSSION;213
10;PART 3: THE UTILIZATION OF REDUCING POWER;218
10.1;CHAPTER 13. RELATIONSHIPS BETWEEN ENERGY-GENERATION AND NET ELECTRON TRANSFER IN BACTERIAL PHOTOSYNTHESIS;220
10.1.1;Light-dependent reduction of fumarate in a model system;222
10.1.2;Effects of uncoupling agents on light-dependent fumarate reduction;224
10.1.3;Photoproduction of molecular hydrogen;227
10.1.4;Concluding remarks;228
10.1.5;REFERENCES;230
10.2;CHAPTER 14. THE ACCUMULATION OF DIVALENT IONS BY ISOLATED MITOCHONDRIA;232
10.2.1;THE ACCUMULATION OF .n++ IN THE PRESENCE AND ABSENCE OF .i;232
10.2.2;INVESTIGATION OF THE Mn ++-EFFECT USING EPR AND PULSED-NMR;237
10.2.3;REFERENCES;243
10.3;DISCUSSION;245
10.4;CHAPTER 15. ... ACCUMULATION IN HEART MITOCHONDRIA;250
10.4.1;REFERENCES;258
10.5;DISCUSSION;259
10.6;CHAPTER 16. CALCIUM-STIMULATED RESPIRATION IN MITOCHONDRIA;266
10.6.1;Discussion;276
10.6.2;SUMMARY;280
10.6.3;ACKNOWLEDGEMENT;281
10.6.4;REFERENCES;281
10.7;DISCUSSION;283
11;INDEX OF PARTICIPANTS;290
12;INDEX TO SUBJECTS;292