Microarray Methods for Drug Discovery

Softcover Nachdruck of the original 1. Auflage 2010
ISBN: 978-1-4939-5739-2
Verlag: Humana

Buch, Englisch, 285 Seiten, Previously published in hardcover, Format (B × H): 178 mm x 254 mm, Gewicht: 561 g

Reihe: Methods in Molecular Biology

Supplies new information on microarrays for cytogenetics and drug metabolism Covers a wide range of microarray platforms used in genomics, epigenomics, genotyping, proteomics, and small molecule screening A good reference for designing microarray experiments to decipher transcriptome regulation and DNA modifications Includes supplementary material: sn.pub/extras

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Chittur, Sridar V.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

Multicenter Clinical Sample Collection for Microarray Analysis.- Isolation of Total RNA from Transgenic Mouse Melanoma Subsets Using Fluorescence-Activated Cell Sorting.- Microarray Analysis of Embryonic Stem Cells and Differentiated Embryoid Bodies.- Determination of Alternate Splicing Events Using the Affymetrix Exon 1.0 ST Arrays.- Profiling microRNA Expression with the Illumina BeadChip Platform.- TaqMan® Array Cards in Pharmaceutical Research.- DMET™ Microarray Technology for Pharmacogenomics-Based Personalized Medicine.- The Use of Microarray Technology for Cytogenetics.- PCR/LDR/Universal Array Platforms for the Diagnosis of Infectious Disease.- RIP-CHIP in Drug Development.- ChIPing Away at Global Transcriptional Regulation.- HELP (HpaII Tiny Fragment Enrichment by Ligation-Mediated PCR) Assay for DNA Methylation Profiling of Primary Normal and Malignant B Lymphocytes.- High-Throughput Screening of Metalloproteases Using Small Molecule Microarrays.- Metabolic Enzyme Microarray Coupled with Miniaturized Cell-Culture Array Technology for High-Throughput Toxicity Screening.- Use of Tissue Microarray to Facilitate Oncology Research.- Small Molecule Selectivity and Specificity Profiling Using Functional Protein Microarrays.- Production and Application of Glycan Microarrays.