Chung / Widdicombe / Boushey Cough

Causes, Mechanisms and Therapy
1. Auflage 2008
ISBN: 978-0-470-75503-7
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 320 Seiten, E-Book

Cough is the most familiar symptom of respiratory disease, and aproblem which general practitioners must deal with on a dailybasis. This timely volume draws together a wealth of recentresearch into the mechanisms, pharmacology and therapies for cough,and places these in clinical context. The text incorporatesguidelines on the most common causes of cough, discusses treatmentsand pitfalls in management, summarizes current research onphysiology, pharmacology and treatment of cough, and givespractical advice on diagnosis and management issues for theclinician.
Cough: Causes, Mechanisms and Therapy is the mostcomprehensive, up-to-date account of the subject. It will updateclinical and basic medical scientists, and promote future research.Readers are encouraged to implement the clinical implications ofthe discussion into routine practice. This volume will appeal toall those involved in the treatment of respiratory disease,particularly those in hospital respiratory units, and will also beof use to interested general practitioners.

Autoren/Hrsg.

Chung, Kian Fan

Widdicombe, John G.

Boushey, Homer A.

Inhaltsverzeichnis

Contributors.
Preface.
Section 1: Introduction.
1 The clinical and pathophysiological challenge of cough.
2 Epidemiology of cough.
3 A brief overview of the mechanisms of cough.
Section 2: Cough in the clinic.
4 Clinical assessment of cough.
5 Measurement and assessment of cough.
6 Cough sensitivity: the use of provocation tests.
7 Causes, assessment and measurement of cough in children.
8 The quality of life in coughers Section 3: Clinicalconditions with cough.
9 Cough in lower airway infections.
10 Cough in gastro-oesophageal reflux.
11 Cough in postnasal drip, rhinitis and rhinosinusitis.
12 Cough and airway hyperresponsiveness.
13 Cough in chronic obstructive pulmonary disease (COPD).
14 Cough in suppurative airway diseases.
15 Cough in cancer patients.
.
Section 4: Pathophysiology.
16 Sensory pathways for the cough reflex.
17 Neurogenesis of cough.
18 Plasticity of vagal afferent fibres mediating cough.
19 Motor mechanisms and the mechanics of cough.
20 Mucus hypersecretion and mucus clearance in cough.
21 Animal models of cough.
Section 5: Therapy.
22 Mechanisms of actions of centrally acting antitussives -electrophysiological and neurochemical analysis.
23 Pharmacology of peripherally acting antitussives.
24 Current and potential future antitussive therapies.
25 Placebo effects of antitussive treatments on cough associatedwith acute upper respiratory tract infection.
26 Mucoactive agents for the treatment of cough.
27 Management of cough.
Index