Craig / Reading Thermal Analysis of Pharmaceuticals

1. Auflage 2010
ISBN: 978-1-4200-1489-1
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 416 Seiten

As a result of the Process Analytical Technologies (PAT) initiative launched by the U.S. Food and Drug Administration (FDA), analytical development is receiving more attention within the pharmaceutical industry. Illustrating the importance of analytical methodologies, Thermal Analysis of Pharmaceuticals presents reliable and versatile characterization tools for the successful development of pharmaceutical products. It draws attention to the most widely applicable methods and demonstrates how to interpret the associated data. The book opens with the first three chapters devoted to differential scanning calorimetry (DSC), the most commonly used thermal method. These chapters cover the principles, optimal use, and pharmaceutical applications of the method. Subsequent chapters explore modulated temperature DSC, thermogravimetric analysis, thermal microscopy, microcalorimetry, high sensitivity DSC, dynamic mechanical analysis, and thermally stimulated current, all of which have attracted great interest within the pharmaceutical field. The chapters include theoretical background, measurement optimization, and pharmaceutical applications of each technique. Exploring important techniques for characterizing the physical structure and properties of pharmaceutical materials, Thermal Analysis of Pharmaceuticals achieves an ideal balance in the depth, relevance, and accessibility of topics presented. The book provides an excellent overview of this key area in pharmaceutical development.

Zielgruppe

Pharmaceutical scientists in academia and in industry especially working in formulation science and analytical science, analytical chemists working in pharmaceutical industry, Ph.D. students and analytical chemists working in thermal analysis field, and advanced undergraduates in pharmacy.

Autoren/Hrsg.

Craig, Duncan Q.M.

Reading, Mike

Fachgebiete

• Naturwissenschaften Chemie Analytische Chemie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie

Inhaltsverzeichnis

Principles of Differential Scanning Calorimetry

Mike Reading and Duncan Q.M. Craig

Optimizing DSC Experiments

Trevor Lever

Pharmaceutical Applications of DSC

Duncan Q.M. Craig

Modulated Temperature Differential Scanning Calorimetry

Mike Reading, Duncan Q.M. Craig, John R. Murphy, and Vicky L. Kett

Thermogravimetric Analysis: Basic Principles

Andrew K. Galwey and Duncan Q.M. Craig

Thermogravimetric Analysis: Pharmaceutical Applications

Duncan Q.M. Craig and Andrew K. Galwey

Thermal Microscopy

Imre M. Vitez and Ann W. Newman

Principles and Pharmaceutical Applications of Isothermal

Microcalorimetry

Graham Buckton

High-Sensitivity Differential Scanning Calorimetry

Simon Gaisford

Thermorheological (Dynamic Oscillatory) Characterization of

Pharmaceutical and Biomedical Polymers

David S. Jones

The Use of Thermally Stimulated Current Spectroscopy in the

Pharmaceutical Sciences

N. Boutonnet-Fagegaltier, A. Lamure, J. Menegotto, C. Lacabanne, A. Caron, H. Duplaa, and M. Bauer Index