E-Book, Englisch, 264 Seiten
Daoud Cancer Proteomics
1. Auflage 2007
ISBN: 978-1-59745-169-7
Verlag: Humana Press
Format: PDF
Kopierschutz: 1 - PDF Watermark
From Bench to Bedside
E-Book, Englisch, 264 Seiten
Reihe: Cancer Drug Discovery and Development
ISBN: 978-1-59745-169-7
Verlag: Humana Press
Format: PDF
Kopierschutz: 1 - PDF Watermark
This book covers current topics related to the use of proteomic strategies in cancer therapy as well as anticipated challenges that may arise from its application in daily practice. It details current technologies used in proteomics, examines the use proteomics in cell signaling, presents clinical applications of proteomics in cancer therapy, and looks at the role of the FDA in regulating the use of proteomics.
Autoren/Hrsg.
Weitere Infos & Material
1;Preface;6
2;Contents;9
3;Contributors;11
4;I Proteomics Technologies;13
4.1;1 Current and Emerging Mass Spectrometry Instrumentation and Methods for Proteomic Analyses;14
5;II Cell Signaling Proteomics;47
5.1;2 Integration of Genomics and Proteomics in Dissecting p53 Signaling;48
5.2;3 Proteomic Profiling of Tyrosine Kinases as Pharmacological Endpoints for Targeted Cancer Therapy;67
6;III Tumor Proteomics;86
6.1;4 Oncoproteomics for Personalized Management of Cancer;87
6.2;5 Application of Serum and Tissue Proteomics to Understand and Detect Solid Tumors;106
6.3;6 Insight on Renal Cell Carcinoma Proteome;126
6.4;7 Proteomics in Lung Cancer;143
6.5;8 Proteomic Strategies of Therapeutic Individualization and Target Discovery in Acute Myeloid Leukemia;164
6.6;9 New Tumor Biomarkers;191
7;IV Bioinformatics and Regulatory Aspects of Proteomics;210
7.1;10 Annotating the Human Proteome;211
7.2;11 Regulatory Issues in the Co-Development of Oncology Drugs and Proteomic Tests: An Overview;236
8;Index;258
