Dawson Quadrupole Mass Spectrometry and Its Applications

1. Auflage 2013
ISBN: 978-1-4831-6504-2
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 372 Seiten, Web PDF

Quadrupole Mass Spectrometry and Its Applications provides a comprehensive discussion of quadrupoles and their applications. It proceeds from a general explanation of the action of radiofrequency quadrupole fields to the description of their utilization in mass analyzers-such as the quadrupole mass filter, the monopole, the three-dimensional quadrupole ion trap, and various time-of-flight spectrometers-and finally to the characteristic applications of quadrupoles. A multi-author format has been adopted to provide broader-than-usual viewpoint in the book. The book begins by explaining the principles of operation of quadrupole devices. These include ion trajectories and computer simulations of performance; analytical theory; numerical methods of calculation of performance, including the recently developed application of phase-space dynamics; and fringing fields and other field imperfections. Subsequent chapters provide design and performance evaluations of the mass filter, the monopole, ion traps, and time-of-flight instruments; and describe areas of application where quadrupole devices have made the greatest impact because of their particular advantages and disadvantages.

Autoren/Hrsg.

Dawson, Peter H.

Inhaltsverzeichnis

1;Front Cover;1
2;Quadrupole Mass Spectrometry and its applications;4
3;Copyright Page;5
4;Table of Contents;8
5;Dedication;6
6;Preface;16
7;PRINCIPAL SYMBOLS;20
8;CHAPTER I. INTRODUCTION;24
8.1;REFERENCES;29
9;CHAPTER II PRINCIPLES OF OPERATION;32
9.1;A. THE QUADRUPOLE FIELD;32
9.2;B. THE MASS FILTER;42
9.3;C. THE MONOPOLE;60
9.4;D. THE QUADRUPOLE ION TRAP;69
9.5;E. EXACT FOCUSSING DEVICES;80
9.6;F. THE OSCILLATORY FIELD TIME-OF-FLIGHT SPECTROMETER;84
9.7;G. STATIC QUADRUPOLE DEVICES;85
9.8;REFERENCES;86
10;CHAPTER III. ANALYTICAL THEORY;88
10.1;A. THE HILL EQUATION;89
10.2;B. THE MATHIEU EQUATION;92
10.3;C. THE COMPLETE SOLUTION;95
10.4;D. AUXILIARY FIELDS;97
10.5;E. SPECIAL CASES;99
10.6;REFERENCES;100
11;CHAPTER IV. NUMERICAL CALCULATIONS;102
11.1;A. NUMERICAL INTEGRATION;103
11.2;B. MATRIX METHODS;106
11.3;REFERENCES;115
12;CHAPTER V. FRINGING FIELDS AND OTHER IMPERFECTIONS;118
12.1;A. FRINGING FIELDS;119
12.2;B. SYSTEMATIC FIELD FAULTS;132
12.3;REFERENCES;142
13;CHAPTER VI. THE MASS FILTER: DESIGN AND PERFORMANCE;144
13.1;A. BASIC CONSIDERATIONS OF MASS RANGE AND RESOLUTION;144
13.2;B. FIELD IMPERFECTIONS AND THEIR EFFECT ON PERFORMANCE;148
13.3;C. THE ION SOURCE;154
13.4;D. ION DETECTION;159
13.5;E. INSTRUMENT SENSITIVITY;164
13.6;F. OPERATION WITH NON-SINUSOIDAL FIELDS;167
13.7;G. ELECTRICAL POWER SUPPLIES;168
13.8;REFERENCES;174
14;CHAPTER VII. THE MONOPOLE: DESIGN AND PERFORMANCE;176
14.1;A. INTRODUCTION;176
14.2;B. ION OSCILLATIONS IN A MONOPOLE;176
14.3;C. ION ENTRANCE AND EXIT;181
14.4;D. MECHANICAL CONSTRUCTION OF THE MONOPOLE;182
14.5;E. THE POWER SUPPLY;184
14.6;F. COMPARISON OF THE EXPERIMENTAL OBSERVATIONS WITH THEORETICAL EXPECTATIONS;187
14.7;G. EFFECT OF A HIGH PRESSURE IN THE MONOPOLE SECTION;199
14.8;H. NEGATIVE IONS;199
14.9;I. POWER CONSUMPTION;201
14.10;J. CONCLUSIONS;202
14.11;REFERENCES;203
15;CHAPTER VIII. QUADRUPOLE ION TRAPS;204
15.1;A. INTRODUCTION;204
15.2;B. THE THREE-ELECTRODE ION TRAP. CONSTRUCTION ANDINSTRUMENTATION;205
15.3;C. OTHER FORMS OF ION TRAP;213
15.4;D. SURVEY OF APPLICATIONS OF ION TRAPS;218
15.5;REFERENCES;245
16;CHAPTER IX. TIME-OF-FLIGHT SPECTROMETERS;248
16.1;A. INTRODUCTION;248
16.2;B. PRINCIPLE OF OPERATION;249
16.3;C. ION DISPLACEMENT;250
16.4;D. ARRIVAL TIME;253
16.5;E. RESOLUTION;254
16.6;F. EXPERIMENTAL RESULTS;256
16.7;H. NEW MODES OF OPERATION;259
16.8;I. CONCLUSIONS;262
16.9;REFERENCES;262
17;CHAPTER X. APPLICATIONS IN ATOMIC AND MOLECULAR PHYSICS;264
17.1;A. GENERAL APPLICATIONS;264
17.2;B. SPECIAL APPLICATIONS;280
17.3;REFERENCES;290
18;CHAPTER XI. APPLICATIONS TO UPPER ATMOSPHERE RESEARCH;296
18.1;A. EARLY HISTORY OF MASS SPECTROMETRIC MEASUREMENTS IN THE UPPER ATMOSPHERE;296
18.2;B. THE UPPER ATMOSPHERE OF THE EARTH;300
18.3;C. TECHNIQUES OF IN SITU MEASUREMENTS;300
18.4;D. RECENT QUADRUPOLE APPLICATIONS AND DEVELOPMENTS;304
18.5;REFERENCES;307
19;CHAPTER XII. APPLICATIONS TO GAS CHROMATOGRAPHY;310
19.1;A. INTRODUCTION;310
19.2;B. GAS CHROMATOGRAPHY-QUADRUPOLE MASS SPECTROMETRY INSTRUMENTAL DEVELOPMENTS;310
19.3;C. AUTOMATION;319
19.4;D. NEW TECHNIQUES;320
19.5;E. CONCLUSION;327
19.6;REFERENCES;329
20;CHAPTER XIII. MEDICAL AND ENVIRONMENTAL APPLICATIONS;330
20.1;A. MEDICAL APPLICATIONS;330
20.2;B. ENVIRONMENTAL MONITORING;342
20.3;C. CONCLUSIONS;351
20.4;REFERENCES;354
21;APPENDICES;358
21.1;APPENDIX: A;358
21.2;APPENDIX: B;359
21.3;APPENDIX: C;360
21.4;APPENDIX: D;361
21.5;APPENDIX: E;362
21.6;APPENDIX: F;363
22;INDEX;368