Dibaba / Kriek / Thoen Tuberculosis in Animals: An African Perspective

1. Auflage 2019
ISBN: 978-3-030-18690-6
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 453 Seiten

This book recounts the biology of M. bovis, followed by the status of bovine Tuberculosis (bTB) in African countries, primarily based on zoonotic and epidemiological field reports. Since the accumulation of data is valueless unless it led to practicable control measures, emphasis is put on locally adapted protocols for future control of the disease. In order to systematically evaluate the knowledge base of bTB, Epidemiologic Problem Oriented Approach (EPOA) methodology was used. The methodology is composed of two triads: i) the problem identification/characterization triad, which is mainly descriptive in nature, and ii) the problem management/solution/mitigation triad, which is mainly geared toward problem management/solution (see figure). The first triad comprises three pillars: i) agent ii) host, and iii) environment and the second one: i) therapeutics/treatment, ii) prevention/control, and iii) health maintenance/promotion. The two triads are linked together by the diagnostic procedure linkage. The systematic and detailed studies of the 'Host-Agent-Environment' interactions are the building blocks to the understanding of agent transmission pathways and disease spread. These may include data about the disease status of the country, the nature of the disease agent and its hosts, the modes of transmission, the wildlife reservoirs in nature, persistence of infection, and agent survival in animal products and the environment. The problem identification and characterization triad identifies these interactions. Once a problem has been identified and well understood, the next step is to minimize the risk of transmission and spread of a disease. This area, referred to as problem solution/management triad, consists of problem management alternatives that rely upon prevention/control, and health maintenance/promotion of the disease in livestock, wildlife, and humans with the emphasis on resource-poor, developing countries in Africa.

Prof. Asseged Bogale Dibaba Center for Computational Epidemiology, Bioinformatics and Risk Analysis College of Veterinary Medicine, Nursing and Allied Health Tuskegee University, Tuskegee, AL 36088. Tel. [phone] Fax. [phone] Research Area: Import/export risk analysis with regard to the introduction of exotic disease agents into USA along with importation of animals and animal products. The products may range from conventional products such as live animals, meat, milk, hides, etc... to non-conventional products such as embryos and embryo-clones. The focus of research on bovine tuberculosis (bTB) is to provide an improved understanding of risk factors associated with disease transmission and maintenance, such as various host, agent, and environmental factors, including level and type of animal husbandry practices. The ultimate goal is to elucidate the economic and public health significance of bTB caused by M. bovis and recommend locally-adapted measures to control the disease, both in human and animal populations.Prof. Asseged Bogale Dibaba Center for Computational Epidemiology, Bioinformatics and Risk Analysis College of Veterinary Medicine, Nursing and Allied Health Tuskegee University, Tuskegee, AL 36088. Tel. [phone] Fax. [phone] Research Area: Import/export risk analysis with regard to the introduction of exotic disease agents into USA along with importation of animals and animal products. The products may range from conventional products such as live animals, meat, milk, hides, etc... to non-conventional products such as embryos and embryo-clones. The focus of research on bovine tuberculosis (bTB) is to provide an improved understanding of risk factors associated with disease transmission and maintenance, such as various host, agent, and environmental factors, including level and type of animal husbandry practices. The ultimate goal is to elucidate the economic and public health significance of bTB caused by M. bovis and recommend locally-adapted measures to control the disease, both in human and animal populations.Prof. Charles O. Thoen DVM, PhD., Diplomate AVES Professor Vet Microbiology & Preventive Medicine College of Veterinary Medicine Iowa State University Ames, Iowa 50011 USA (Deceased).  Vet Med Expertise / Research Area Dr. Thoen conducted investigations on the pathogenesis of Mycobacterium bovis, M. tuberculosis, M. avium ss paratuberculosis, M. avium ss avium and M. avium ss intracellulare in domestic and captive wild animals. The focus of research was to provide an improved understanding of host immune responses that can be used in developing more reliable in vivo and in vitro diagnostic tests.

Autoren/Hrsg.

Dibaba, Asseged B.

Kriek, Nicolaas P. J.

Thoen, Charles O.