E-Book, Englisch, 158 Seiten
Dikic Endosomes
1. Auflage 2008
ISBN: 978-0-387-39951-5
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, 158 Seiten
Reihe: Molecular Biology Intelligence Unit
ISBN: 978-0-387-39951-5
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
Endosomes are a heterogeneous population of endocytic vesicles and tubules that have captivated the interest of biologists for many years, partly due to their important cellular functions and partly due to their intriguing nature and dynamics. Endosomes represent a fascinating interconnected network of thousands of vesicles that transport various cargoes, mainly proteins and lipids, to distant cellular destinations. How endosomes function, what co-ordinates the molecular determinants at each step of their dynamic life cycle and what their biological and medical relevance is, are among the questions addressed in this book.
Autoren/Hrsg.
Weitere Infos & Material
1;CONTENTS;5
2;EDITOR;8
3;CONTRIBUTORS;8
4;PREFACE;10
5;Endosomes Come of Age;11
6;Upid Membrane Domains in Endosomes;24
7;Rab Domains on Endosomes;33
8;Synaptic Endosomes;46
9;Endosome Fusion;60
10;Clathrin Adaptor Proteinsin Cargo Endocytosis;72
11;Protein Sorting in Endosomes;86
12;Signaling from Internalized Receptors;99
13;Endocytosis of Receptor Tyrosine Kinases: Implications for Signal Transduction by Growth Factors;111
14;Endocytic Trafficking and Human Diseases;129
15;Endosomes - Key Components in Viral Entry and Replication;142
16;Toxins in the Endosomes;155
17;Index;163
