Dössel World Congress on Medical Physics and Biomedical Engineering September 7 - 12, 2009 Munich, Germany

Vol. 25/VIII Micro- and Nanosystems in Medicine, Active Implants, Biosensors
1. Auflage 2010
ISBN: 978-3-642-03887-7
Verlag: Springer
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 390 Seiten

Present Your Research to the World! The World Congress 2009 on Medical Physics and Biomedical Engineering - the triennial scientific meeting of the IUPESM - is the world's leading forum for presenting the results of current scientific work in health-related physics and technologies to an international audience. With more than 2,800 presentations it will be the biggest conference in the fields of Medical Physics and Biomedical Engineering in 2009! Medical physics, biomedical engineering and bioengineering have been driving forces of innovation and progress in medicine and healthcare over the past two decades. As new key technologies arise with significant potential to open new options in diagnostics and therapeutics, it is a multidisciplinary task to evaluate their benefit for medicine and healthcare with respect to the quality of performance and therapeutic output. Covering key aspects such as information and communication technologies, micro- and nanosystems, optics and biotechnology, the congress will serve as an inter- and multidisciplinary platform that brings together people from basic research, R&D, industry and medical application to discuss these issues. As a major event for science, medicine and technology the congress provides a comprehensive overview and in-depth, first-hand information on new developments, advanced technologies and current and future applications. With this Final Program we would like to give you an overview of the dimension of the congress and invite you to join us in Munich! Olaf Dössel Congress President Wolfgang C.

Autoren/Hrsg.

Dössel, Olaf

Inhaltsverzeichnis

1;IFMBE 25/VIII;1
2;Preface;5
3;Table of Contents;8
4;Silicon Eye;16
5;Automated Assembly of Dynamic Micro-Bead Arrays Using a Multi-arm Laser Manipulator with Computer Vision;20
6;A Nano-porous Aerogel Biochip for Molecular Recognition of Nucleotide Acids;23
7;Biodegradable Polymeric Implants as Drug Delivery Systems for Brain Cancer Therapy;26
8;CH2-Symmetric/CH2-Antisymmetric Stretch Ratio Sensor for Cell Analysis;30
9;Optimization of Ligand Surface Concentration for Biosensor based on Imaging Ellipsometry;34
10;Are Defibrillation Thresholds Ruled by a Hyperbolic Strength Duration Relationship?;37
11;Development of a Patient Controlled, Telemetric Bolus System for an Implantable Infusion Pump;41
12;Finite Element Modelling of Microphysiometry on Cellular Specimen;45
13;CD146 detection with real-time total internal reflection imaging ellipsometry;49
14;Space saving Mixed Signal FPGAs for improving processing power and memory capacity as a replacement for µCs in portable biosensor devices;52
15;Nanomaterial based electrochemical transducing platforms for biomedical applications;56
16;Sensor chips for multiparametric real time monitoring of cell metabolism and drug response;60
17;Microfluidic platform for the initiation and investigation of cellular interactions on a single-cell level;64
18;ESOPHAGEAL FLOW CONTROL MODULE FOR TREATMENT OF OBESITY;68
19;Basic Concepts for Active Implantable Valve Development;72
20;Estimation of Magnetic Nanoparticle Diameter with a Magnetic Particle Spectrometer;76
21;Fate of drug loaded-LNCs in cell culture medium – impact on drug delivery strategies;80
22;Speeding up sensor response times by modifying the geometry of the fluidic channel of a disposable array compatible sensor housing for surface acoustic wave biosensors;84
23;Surface Acoustic Wave (SAW) Biosensor Chip System – a Promising Alternative for Biomedical Applications;88
24;Multiparametric NeuroLab with integrated MEA & life support;92
25;QCM BASED ON FLOW SYSTEM FOR CARDIOVASCULAR DISEASE;95
26;Automated 24 well neuro-screening system with life support;99
27;Manufacture of SU-8 Micro-Grippers for Mechanical Characterization of Gut Epithelial Cells;102
28;Mathematical methods for interpretation of metabolic signals from living cells on biohybrid sensor chips;106
29;Electroactive Nanoporous Valve for Controlled Drug Delivery;110
30;Fieldbus controlled live support system for cell-based biohybrid measuring systems;113
31;Traveling-wave electrohydrodynamics: a versatile method for collecting nanoscaled objects from fluids;116
32;Preparation of functional magnetic cationic polymeric liposomes via a simple process;119
33;Fluorescent Gold Nanoclusters for Biomedical Applications;123
34;Microelectrode Array (MEA) high resolution electrophysiological mapping of cardiac cell, tissue and organ preparations;127
35;$\alpha$-fetoprotein analysis in human serum through quartz crystal microbalance;131
36;Development of a generic multiple frequency signal generator for BioMEMS;135
37;Precise Deposition of Electrospun Nanofibers and Electrospraying of Nanoparticles as Enabling Techniques for Biomedical Engineering Applications;139
38;Nanomaterials for Positive Contrast Imaging of MR-Visible Implants;143
39;Femtosecond Laser Microstructuring and Bioactivation of Titanium Surfaces forMiddle Ear Ossicular Replacement Prosthesis;147
40;Automation of Chemosensitivity Testing - Enabling Personalized Cancer Therapy;151
41;A novel fabrication route to integrating label-free detection of DNA hybridization in microfluidic channel;155
42;Concept of a Microfluidics and Tunneling Effect-Based BioMEMS to Detect Cells;159
43;Simulation of Drug Release for the Development of Drug-Eluting Stents – Influence of Design and Manufacturing Parameters on Drug Release Kinetics;163
44;Application of an Electronic Nose to Diagnose Liver Cirrhosis from the Skin Surface;165
45;Development and Fabrication of Multielectrode Arrays for Immuno-Assisted Whole Cell Detection Systems;168
46;Sample Preparation on-chip: Accumulation, Lysis of and DNA Extraction from Bacteria;172
47;Towards Artificial Liver Sinusoids by Dielectrophoretic Cell Assembly in Microfluidic System for Use in Substance Screening;176
48;Application of Supported Phospholipids Bilayers for Biosensor based on Imaging Ellipsometry;180
49;Chitosan cushioned air stable single PEGylated phospholipid bilayers ;184
50;Application of Carbonyl Iron Powder as a Novel Mediator for ArterialEmbolization Hyperthermia— Feasibility Investigation;187
51;Development of a Multifunctional Microfluidic System for Studies of Nerve Cell Activity during Hypoxic and Anoxic Conditions;191
52;A Novel Microfluidic Based Technique for Encapsulation of Langerhans´ Islets Using High Viscosity Alginate and BaSO4 Nanoparticles;195
53;Analysis of chemotactic activity of mammalian cells in a microfluidic device;198
54;An Adjustable Optofluidic Micro Lens Enhancing Single Cell Analysis Systems;200
55;Artificial urinary bladder – focal technical challenges;204
56;Design and Performance of an improved active subretinal chip;207
57;An intelligent implant system for monitoring and biofeedback therapy of snoring;211
58;Driving force of a neutrophile in liquid using concentration Marangorni effect for developing microcapsule for Drug Delivery Systems;215
59;Cellular Uptake of Gold Nanoparticles into Normal and Cancer Cells;217
60;Study to trap fluid microcapsules in artificial blood vessel by producing local acoustic radiation force;221
61;Diamond microelectrodes for amperometric detection of secretory cells activity;223
62;Local electrical stimulation of single myocytes using three-dimensional electrode arrays with small interelectrode distances;227
63;On-Surface Amplification of L-Glutamate Using a Patterned Bi-enzymatic System;231
64;The role of microrheological red blood cell properties in efficiency of drug transport and their delivery to cellular targets;235
65;A polymer based local drug delivery system on plasma activated silicon implant surfaces;238
66;Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging;241
67;Size depended electrical properties of Hydroxyapatite nanoparticles ;245
68;Microscale Organization of Chondrocyte Array in Hydrogel by Dielectrophoresis;248
69;Iron oxide nanoparticles conjugated with trastuzumab as an immunospecific probe for detecting HER2 antigen;250
70;Determination of Tannic Acid Precipitated with Bovine Serum Albumin by Visible Light Scattering by a Flow-injection System;252
71;Magnetron Enhanced Plasma-Polymerization for Biocompatible Sensor Coatings and Membranes on Polymeric Based Materials;256
72;Fully electronic cellular migration assays with field-effect transistor arrays;257
73;Artificial Urinary Diversion System – kinematic requirements on fixation;260
74;Compact Drug Delivery System for Analysis Arrays;263
75;Effect of Polymer Molecular Weight on Morphology and Particle Size of Chitosan Microspheres Prepared via Spray Drying Method;266
76;The Use of Body Motion for Powering Biomedical Devices;268
77;Economic feasibility studies in the field of Active Implants and Biosensors over Simulations: A methodology for structured and valid results;272
78;Dual phosphatidylglyceroglycerol-based thermosensitive liposomes for MR-guided chemothermotherapy;274
79;Monitoring adherent cell cultures in microtiter-plates by a wireless sensory system;276
80;In-vitro characterization of an implantable thermal flow sensor for hydrocephalus;280
81;Concentration-dependent multi-parametric functional screening of CNS drugs with neuronal networks on microelectrode arrays;284
82;Electric Field Characteristics of Bipolar Impedance Sensors;288
83;Hemodynamic response with an artificial myocardial assistance in chronic animal examination;292
84;Implantable sensor system for the monitoring of bone healing;296
85;Spontaneous Activity of Rat Embryonic Cardiac Myocytes;300
86;The Design and Construction of a Set of Modular Synthetic BioLogic Devices for Programming Cells;304
87;An Innovative Rotational Magnetic System to Enhance Cell Transfection with Magnetic Nanoparticles;308
88;PROTMINE: A Web Service Based Tool to Interpreter Clinical Proteomic Data;312
89;Silicon Based Multi Parametric Biohybrid Microsensor Chips;314
90;Stent-Based Plasmid Gene Delivery into Porcine Coronary Artery;318
91;Disruption of Microvessels by Focused Ultrasound with Microbubbles to Cause the Extravasation of Macromolecules and Observed by Two-photon Fluorescence Microscopy;321
92;Micro– and Nanosensors for Medical Applications;325
93;Ferroelectric Nanoparticles for Contrast Enhancement Microwave Tomography: Feasibility Assessment for Detection of Lung Cancer.;326
94;MEA Neurosensor, the Tool for Synaptic Activity Detection: Acute Amyloid-ß Oligomers Synaptotoxicity Study;329
95;Development of Tri-component Copolymer Rods as Implantable Drug Delivery Systems for Liver Cancer Therapy;332
96;Microchip-Integrated EOSCs (Electrolyte Oxide Semiconductor Capacitors) as Devices for High Efficiency and Selective Electroporation of Mammalian Cells;336
97;Sensors for Healthcare Monitoring – Proteins, Viruses and Blood-Group-Typing;340
98;The interaction between charged macroions induced by rod-like ions;344
99;Integration of Micro Fluidic Bio-chip Design and Automatic fluorescent Identification for Rapid Sperm Mobility Assessment;347
100;Interfacing metallic ohmic contacts in biocompatible ceramic substrates with diamond surfaces for biosensing applications;351
101;Chemical Modification of Surfaces for Biochemical and Medical Sensor Applications;354
102;Minimizing Stress Exposure to Cells Using Novel Microfluidic Cell Capture Devices;358
103;Development of EGFR-Targeting Nanomedicine for Effectively and Noninvasively Treats Lung Cancer Patients by Aerosol Delivery;362
104;Amperometric Microbiosensors Based on PQQ-Dependent Glucose Dehydrogenase towards the Development of an ATP Biosensor for in vitro Analysis;366
105;Remote Controlled Drug Release Induced by a Rotating Magnetic Field;370
106;Microfluidics for Drug Delivery;374
107;Cell Based Assays for Label Free Investigation of Living Cells;378
108;Silicon Based Devices for Intracellular applications;380
109;Cell Select – A New Concept for Collecting of Rare Cell Populations in vivo;384
110;Combined AFM-SECM: Towards a novel platform for imaging microbiosensors;387
111;Microfluidic Platform for Investigating Small Blood Vessels;391
112;Characterization of Electron Conduction in Unsaturated Organic Monolayers on Silicon(111) Using Electrical Impedance Spectroscopy;393
113;The study of micro liter Insulin injection system by Osmotic pressure for Diabetes therapy;397
114;Amperometric Monitoring of Substance-P Levels in Biological Fluids;399
115;High Throughput Microelectrode Array Platforms for Quantitative Pharmacology, Toxicology, and Drug Development Using Spontaneously Active Neural Tissue;400
116;Author Index;401