Drenth Principles of Protein X-Ray Crystallography

3rd Auflage 2007
ISBN: 978-0-387-33746-3
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 332 Seiten, eBook

Zielgruppe

Graduate

Autoren/Hrsg.

Drenth, Jan

Inhaltsverzeichnis

Crystallizing a Protein.- X-ray Sources and Detectors.- Crystals.- Theory of X-ray Diffraction by a Crystal.- Average Reflection Intensity and Distribution of Structure Factor Data.- Special Forms of the Structure Factor.- The Solution of the Phase Problem by the Isomorphous Replacement Method.- Phase Improvement.- Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Configuration.- Molecular Replacement.- Direct Methods.- Laue Diffraction.- Refinement of the Model Structure.- The Combination of Phase Information.- Checking for Gross Errors and Estimating the Accuracy of the Structural Model.- Practical Protein Crystallization.

Über Autor(innen)

Dr. Jan Drenth is a professor emeritus at the Laboratory of Biophysical Chemistry at the University of Groningen, The Netherlands.Contributing author Dr. Jeroen R. Mesters Ph.D. is a Senior Research Assistant at the Institute of Biochemistry, University of Luebeck, Germany.