Florkin / Stotz Water-Soluble Vitamins, Hormones, Antibiotics

1. Auflage 2014
ISBN: 978-1-4832-2214-1
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band Volume 11, 258 Seiten, Web PDF

Reihe: Comprehensive Biochemistry

Comprehensive Biochemisty, Volume 11: Water-Soluble Vitamins, Hormones, Antibiotics deals with the organic and physical chemistry of the major organic constituents of living material. This book provides a sound treatment of the important biological high polymers, emphasizing their shape and physical properties. A number of substances peculiar to plants, certain isoprenoids, flavonoids, tannins, lignins, and plant hormones are also covered. This publication likewise discusses the fate of thiamine in living organisms, biologically active isoalloxazines, and auxins with a heterocyclic ring system. Other topics include the yolk-formation hormone of the corpora allata, biochemical aspect of the antibiotics, and miscellaneous antibiotics derivable from amino acids. This volume is a good source for biochemists and specialists conducting work on water-soluble vitamins, hormones, and antibiotics.

Autoren/Hrsg.

Florkin, Marcel

Stotz, Elmer H.

Inhaltsverzeichnis

1;Front Cover;1
2;Water-Soluble Vitamins, Hormones, Antibiotics;6
3;Copyright Page;3
4;Table of Contents;11
5;CONTRIBUTORS TO THIS VOLUME;7
6;GENERAL PREFACE;9
7;PREFACE TO SECTION II;10
8;Part A: WATER-SOLUBLE VITAMINS;18
8.1;Chapter I.
Thiamine;20
8.1.1;1. Discovery and isolation;20
8.1.2;2. Occurrence;21
8.1.3;3. Structure;21
8.1.4;4. Synthesis;24
8.1.5;5. The fate of thiamine in living organisms;27
8.1.6;6. Chemical and physical properties;29
8.1.7;7. Methods of assay;30
8.1.8;8. Function and mechanism of action;34
8.1.9;9. Essential groups in the molecule; antithiamines;36
8.1.10;REFERENCES;38
8.2;Chapter II: Riboflavin and Closely Related Flavins;40
8.2.1;1. Isolation;40
8.2.2;2. General chemical and physical properties;41
8.2.3;3. Characterization of riboflavin;42
8.2.4;4. Synthesis of riboflavin and related biologically active flavins;43
8.2.5;5. Biologically active isoalloxazines;47
8.2.6;REFERENCES;51
8.3;Chapter III. Niacin;53
8.3.1;1. Nomenclature;53
8.3.2;2. History;53
8.3.3;3. Chemistry, determination of structure and properties;54
8.3.4;4. Isolation;56
8.3.5;5. Synthesis21,29;57
8.3.6;6. Properties and synthesis of some related compounds of biochemical importance15,21,39;59
8.3.7;7. Methods of determination;60
8.3.8;REFERENCES;63
8.4;Chapter IV. Vitamin B6;65
8.4.1;1. Discovery and structure;65
8.4.2;2. Synthesis;66
8.4.3;3. Properties;68
8.4.4;4. Metabolic degradation;74
8.4.5;REFERENCES;75
8.5;Chapter V. Pantothenic Acid;76
8.5.1;REFERENCES;81
8.6;Chapter VI. Biotin;83
8.6.1;1. Introduction;83
8.6.2;2. Structure determination;84
8.6.3;3. Synthesis of biotin;86
8.6.4;4. Compounds related to biotin;91
8.6.5;ACKNOWLEDGEMENT;96
8.6.6;REFERENCES;97
8.7;Chapter VII. Folic Acid and Pteridines;99
8.7.1;1. Pterins;99
8.7.2;2. Folic acid and related compounds;102
8.7.3;3. Biopterin and related derivatives;112
8.7.4;4. Pteridines related to riboflavin;114
8.7.5;REFERENCES;116
8.8;Chapter VIII. Vitamin B12;120
8.8.1;1. Introduction;120
8.8.2;2. Purification and crystallization of vitamin B12;121
8.8.3;3. Structure;121
8.8.4;4. Nomenclature;126
8.8.5;5. Modifications of vitamin B12;127
8.8.6;6. Coenzyme forms;128
8.8.7;7. Assay;128
8.8.8;REFERENCES;130
9;Part B: HORMONES;132
9.1;Chapter IX. Plant Hormones;134
9.1.1;Section a. Indole Auxins of Plants;134
9.1.1.1;1. Introduction;134
9.1.1.2;2. Auxin synthesis;137
9.1.1.3;3. Indoleacetic acid catabolism;140
9.1.1.4;4. Summary;142
9.1.1.5;REFERENCES;143
9.1.2;Section b. Synthetic Auxins;144
9.1.2.1;1. Introduction;144
9.1.2.2;2. Indole derivatives;145
9.1.2.3;3. Arylalkanecarboxylic acids;147
9.1.2.4;4. Aryloxyalkanecarboxylic acids;149
9.1.2.5;5. Cinnamic acids and related compounds;152
9.1.2.6;6. Hydronaphthoic acids;153
9.1.2.7;7. Substituted benzoic and naphthoic acids;155
9.1.2.8;8. Auxins with a heterocyclic ring system;157
9.1.2.9;9. Auxins without a ring system;158
9.1.2.10;10. Auxins with a polar group different from —COOH;159
9.1.2.11;11. Optically active auxins;160
9.1.2.12;12. Auxin antagonists (Antiauxins);162
9.1.2.13;13. Auxin synergists;164
9.1.2.14;14. Summary;165
9.1.2.15;REFERENCES;166
9.1.2.16;REFERENCES ADDED IN PROOF;167
9.1.3;Section c. Gibberellins;168
9.1.3.1;1. Introduction;168
9.1.3.2;2. Physical and chemical properties;170
9.1.3.3;REFERENCES;175
9.1.4;Section d. Purines and Other Compounds;176
9.1.4.1;1. Introduction;176
9.1.4.2;2. Purines;177
9.1.4.3;3. Kinetin and analogues;179
9.1.4.4;4. Conclusion;182
9.1.4.5;REFERENCES;183
9.2;Chapter X. Insect Hormones;185
9.2.1;1. Survey of insect endocrinology;185
9.2.2;2. The brain hormone;187
9.2.3;3. Ecdysone, the hormone of the prothoracic gland;187
9.2.4;4. The juvenile hormone;190
9.2.5;5. The yolk-formation hormone (metabolic hormone) of the corpora allata;191
9.2.6;6. Pheromones;192
9.2.7;REFERENCES;194
10;Part C: ANTIBIOTICS;196
10.1;Chapter XI. The Antibiotics;198
10.1.1;1. Introduction;198
10.1.2;2. Classification of antibiotics;200
10.1.3;3. Biochemical aspect of the antibiotics;200
10.1.4;4. Chemical nature and biogenesis of antibiotics;201
10.1.5;5. Structure and activity;227
10.1.6;6. Biochemical effects of antibiotics on micro-organisms;229
10.1.7;7. Conclusion;235
10.1.8;REFERENCES;238
11;SUBJECT INDEX;242
12;COMPREHENSIVE BIOCHEMISTRY;255