Gershwin / Vierling / Manns Liver Immunology

Principles and Practice
1. Auflage 2008
ISBN: 978-1-59745-518-3
Verlag: Humana Press
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 486 Seiten

Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. This volume is a must-read for novice and expert alike. In an easy-to-read and thorough format, it covers bacterial, parasitic and viral infections of the liver, autoimmune liver disease, alcoholic and nonalcoholic fatty liver diseases, and transplantation.

Autoren/Hrsg.

Gershwin, M. Eric

Vierling, John M.

Manns, Michael P.

Inhaltsverzeichnis

1;Preface;6
2;Contents;7
3;Contributors;10
4;Contemporary Liver Immunology and Immunopathology;13
5;A Short Primer on Fundamental Immunology;25
6;Role and Function of Liver Sinusoidal Endothelial Cells;35
7;Innate Immune Mechanisms in the Liver;50
8;Antigen Processing and Presentation in the Liver;58
9;Adaptive Immunity in the Liver;69
10;Hepatic NK, NKT, and T Cells;79
11;Cytokines in Liver Health and Disease;91
12;Prevalence and Significance of Autoantibodies in Acute and Chronic Liver Diseases and Hepatocellular Carcinoma;102
13;The Role of Inflammation and Immunity in the Pathogenesis of Liver Fibrosis;118
14;Clinical Use of Immunopathology Techniques in Liver Diseases;129
15;Tumor Immunology;143
16;Innate and Adaptive Immune Responses to Bacterial and Parasite Infections;157
17;Immune Response to Hepatitis A and E Viruses;167
18;Role of the Immune Response in Hepatitis B;182
19;Immune Responses in Acute and Chronic Hepatitis C;195
20;Immunopathogenesis of Extrahepatic Manifestations in HAV, HBV, and HCV Infections;211
21;Immunogenetics of Autoimmune Liver Disease;221
22;Primary Biliary Cirrhosis and Autoimmune Cholangitis;234
23;Sclerosing Cholangitis;247
24;Autoimmune Hepatitis;260
25;Unique Aspects of Autoimmune Hepatitis in Children;273
26;Overlap Syndromes of Autoimmune Hepatitis With Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis;280
27;Animal Models of Autoimmune Liver Diseases;287
28;The Immune Response in the Pathogenesis;302
29;of Alcoholic Liver;302
30;Immunomodulation Therapy for Alcoholic Hepatitis;315
31;Role of Immune Response in Nonalcoholic Fatty Liver Disease;329
32;Mechanisms of Acute Liver Failure;339
33;Immune Mechanisms in Drug-Induced Hepatotoxicity;351
34;Acute and Chronic Liver Diseases Induced by Drugs or Xenobiotics;363
35;Clinical Use of Immunosuppressive Drugs to Control the Immune Response;378
36;Hepatic Complications of Hematopoietic Cell Transplantation;395
37;Acute and Chronic Rejection of the Liver Allograft;408
38;Immunological Tolerance in Allo- and Xenografts;417
39;Autoimmune Diseases in Transplanted Livers;434
40;Immunopathogenesis and Outcomes of Recurrent Hepatitis C;441
41;Index;453