Greaves / Chan Epidemiology of Leukaemia and Lymphoma

Report of the Leukaemia Research Fund International Workshop, Oxford, UK, September 1984
1. Auflage 2013
ISBN: 978-1-4831-5103-8
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 178 Seiten, Web PDF

Epidemiology of Leukaemia and Lymphoma contains the proceedings of the Leukaemia Research Fund International Workshop held in Oxford, UK, on September 25-27, 1984. Contributors explore the epidemiology of leukemia and lymphoma based on the results of a pilot study that investigated whether careful subdivision of acute lymphoblastic leukemia (ALL) using a standardized panel of monoclonal antibodies would reveal interesting associations between subtypes and particular geographic regions or ethnic groups within regions. This book is comprised of 31 chapters divided into four sections and begins with a discussion on epidemiological approaches to hematological malignancy, paying particular attention to international data collection and interpretation; clusters and associations in cancer epidemiology; and childhood leukemia in Great Britain and the Netherlands. The next section explores the causes of human leukemia and lymphoma as well as the epidemiology of leukemia and lymphoma subtypes in various regions of the world such as Africa, Asia, United States, and Mediterranean region. The final section focuses on practical problems in standardized immunophenotyping of leukemias and lymphomas; immuno-alkaline phosphatase labeling of hematological samples; and detection of surface membrane antigens by a rosette assay using antibody coupled red cells. This monograph will be of value to clinicians and medical practitioners interested in the epidemiology of leukemia and lymphoma.

Autoren/Hrsg.

Greaves, M. F.

Chan, L. C.

Inhaltsverzeichnis

1;Front Cover;1
2;Epidemiology of Leukaemia and Lymphoma;4
3;Copyright Page;5
4;Table of Contents;6
5;PREFACE;8
6;PARTICIPANTS;12
7;PART I: EPIDEMIOLOGICAL APPROACHES TO HAEMATOLOGICAL MALIGNANCY;16
7.1;CHAPTER 1. INTERNATIONAL DATA COLLECTION AND INTERPRETATION: A REVIEW;18
7.1.1;CLASSIFICATION;18
7.1.2;MORTALITY STATISTICS;18
7.1.3;MORBIDITY STATISTICS;20
7.1.4;EXAMPLES OF THE USE OF DESCRIPTIVE DATA;21
7.1.5;THE FUTURE;23
7.1.6;REFERENCES;25
7.2;CHAPTER 2. SEARCHING FOR CLUSTERS AND ASSOCIATIONS IN CANCER EPIDEMIOLOGY;26
7.2.1;REFERENCES;27
7.3;CHAPTER 3. DESCRIPTIVE EPIDEMIOLOGY OF CHILDHOOD LEUKAEMIA AND LYMPHOMA IN GREAT BRITAIN;28
7.3.1;REGISTRATION RATES BY AGE AND SEX;28
7.3.2;WHITE BLOOD CELL COUNTS (AND CELLMARKERS);28
7.3.3;HISTOLOGICAL SUBTYPES;30
7.3.4;REFERENCES;31
7.4;CHAPTER 4. RECENT EPIDEMIOLOGICAL. STUDIES OF LEUKAEMIA IN THE UNITED KINGDOM;32
7.4.1;INTRODUCTION;32
7.4.2;LEUKAEMIA RESEARCH FUND STUDIES;32
7.4.3;RESULTS;32
7.4.4;CONCLUSION;39
7.5;CHAPTER 5. EPIDEMIOLOGICAL. AND IMMUNOLOGICAL CHARACTERISTICS OF CHILDHOOD LEUKAEMIA IN THE NETHERLANDS: POPULATION-BASED DATA FROM A NATIONWIDE CO-OPERATIVE GROUP OF PAEDIATRICIANS;40
7.5.1;INTRODUCTION;40
7.5.2;PATIENTS AND METHODS;41
7.5.3;RESULTS;41
7.5.4;DISCUSSION;44
7.5.5;REFERENCES;45
8;PART II: IDENTIFYING CAUSES OF LEUKAEMIA/LYMPHOMA;46
8.1;CHAPTER 6. VIRUSES AS RISK FACTORS OR CAUSES OF HUMAN LEUKAEMIAS AND LYMPHOMAS?;48
8.1.1;INTRODUCTION;48
8.1.2;SERO-EPIDEMIOLOGY OF HTLV-I AND III IN FRENCH WEST INDIES;48
8.1.3;THE EPSTEIN-BARR VIRUS IN THE ETIOLOGY OF BURKITT'S LYMPHOMA;51
8.1.4;REFERENCES;52
8.2;CHAPTER 7. EPIDEMIOLOGY OF HUMAN RETROVIRUSES;54
8.2.1;THE VALUE OF SUBTYPING IN STUDIES OF IRRADIATION AND HUMAN LEUKAEMIA;56
8.2.2;THE MAJOR STUDIES;56
8.2.3;ANALYSIS BY SUBTYPE OF LEUKAEMIA: ANKYLOSING SPONDYLITIS STUDY;56
8.2.4;ANALYSIS BY SUBTYPE OF LEUKAEMIA: LIFE SPAN STUDY;57
8.2.5;CONCLUSIONS;60
8.2.6;REFERENCES;61
8.3;CHAPTER 8. INHERITED FACTORS IN LEUKAEMIA AND LYMPHOMA;62
8.3.1;INHERITED SYNDROMES;62
8.3.2;TWINS;62
8.3.3;FAMILIES;63
8.3.4;INHERITED TRAITS;63
8.3.5;CONCLUSIONS;63
8.3.6;REFERENCES;64
8.4;CHAPTER 9. ANIMAL MODELS: LESSONS FROM FELINE AND BOVINE LEUKAEMIA VIRUS INFECTIONS;65
8.4.1;FELINE LEUKAEMIA VIRUS;65
8.4.2;REFERENCES;67
9;PART III: THE GEOGRAPHY OF LEUKAEMIA AND LYMPHOMA SUBTYPES;68
9.1;CHAPTER 10. COLLABORATIVE GROUP STUDY OF THE EPIDEMIOLOGY OF ACUTE LYMPHOBLASTIC LEUKAEMIA SUBTYPES: BACKGROUND AND FIRST REPORT;70
9.1.1;EPIDEMIOLOGY OF ALL;70
9.1.2;SUBTYPES OF ALL;71
9.1.3;THE COLLABORATIVE GROUP STUDY OF ALL SUBTYPES;73
9.1.4;SUMMARY OF OBSERVATIONS AND PRELIMINARY CONCLUSIONS;81
9.1.5;CENTRES WITH A BIAS IN ALL SUBGROUPS;81
9.1.6;INCREASE IN T-ALL OR DEFICIT IN COMMON ALL?;81
9.1.7;POSSIBLE EXPLANATIONS FOR BIAS IN ALL SUBSETS;81
9.1.8;FURTHER COMMENTS AND CRITICISMS ON THE COLLABORATIVE STUDY AND FUTURE PLANS;84
9.1.9;REFERENCES;85
9.2;CHAPTER 11. THE EPIDEMIOLOGY OF LYMPHOMAS AND LEUKAEMIAS IN AFRICA — AN OVERVIEW;89
9.2.1;INTRODUCTION;89
9.2.2;LYMPHOMAS;89
9.2.3;LEUKAEMIAS;92
9.2.4;REFERENCES;93
9.3;CHAPTER 12. INFLUENCE OF LIFE-STYLE ON THE PATTERN OF LEUKAEMIA AND LYMPHOMA SUBTYPES AMONG NIGERIANS;95
9.3.1;INTRODUCTION;95
9.3.2;METHODS;95
9.3.3;RESULTS;95
9.3.4;DISCUSSION;97
9.3.5;REFERENCES;99
9.4;CHAPTER 13. LEUKAEMIA AND LYMPHOMA IN KENYA;100
9.4.1;THE LEUKAEMIAS;100
9.4.2;THE MALIGNANT LYMPHOMAS;104
9.4.3;BURKITT'S LYMPHOMA;105
9.4.4;REFERENCES;105
9.5;CHAPTER 14. PRELIMINARY COMMUNICATION ON LEUKAEMIA CELL MARKERS IN KENYA;106
9.5.1;I. INTRODUCTION;106
9.5.2;II. PATIENTS;106
9.5.3;III. METHODS;106
9.5.4;IV. RESULTS (SEE TABLE 1);106
9.5.5;DISCUSSION;107
9.5.6;REFERENCES;107
9.6;CHAPTER 15. IMMUNOPHENOTYPIC CLASSIFICATION OF LYMPHOBLASTIC LEUKAEMIA AND LYMPHOCYTIC LYMPHOMA — AN EXPERIENCE IN THE SOUTHWESTERN AREA OF THE CAPE PROVINCE OF SOUTH AFRICA;108
9.6.1;INTRODUCTION;108
9.6.2;MATERIALS AND METHODS;109
9.6.3;RESULTS (TABLE 1);109
9.6.4;DISCUSSION;112
9.6.5;CONCLUSION;115
9.6.6;REFERENCES;115
9.7;CHAPTER 16. ACUTE CHILDHOOD LEUKAEMIA IN JOHANNESBURG;117
9.7.1;ACUTE CHILDHOOD LEUKEMIA IN JOHANNESBURG;117
9.7.2;INCIDENCE;117
9.7.3;ENVIRONMENT AND SOCIO-ECONOMIC STATUS;117
9.7.4;ACUTE LYMPHOBLASTIC LEUKAEMIA;117
9.7.5;ACUTE NON-LYMPHOBLASTIC LEUKAEMIA;118
9.7.6;CONCLUSION;119
9.7.7;REFERENCES;119
9.8;CHAPTER 17. OBSERVATIONS ON THE EPIDEMIOLOGY AND SUBTYPES OF LYMPHATIC MALIGNANCIES IN ISRAEL;120
9.8.1;REFERENCES;121
9.9;CHAPTER 18. CHILDHOOD T-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA IN THE CAMPANIA REGION OF ITALY, 1980–1984;122
9.9.1;REFERENCES;123
9.10;CHAPTER 19. EPIDEMIOLOGY AND IMMUNOLOGICAL PHENOTYPE OF CHILDHOOD ALL IN GREECE*;124
9.10.1;INCIDENCE OF LEUKAEMIA/LYMPHOMA IN GREECE;124
9.10.2;ACUTE LYMPHOBLASTIC LEUKAEMIA SUBTYPES;124
9.10.3;REFERENCES;126
9.11;CHAPTER 20. EPIDEMIOLOGY OF LEUKAEMIAS IN THE PEOPLE'S REPUBLIC OF CHINA;127
9.11.1;I. INCIDENCE;127
9.11.2;II. MORTALITY;127
9.11.3;III. GEOGRAPHIC DISTRIBUTION;127
9.11.4;IV. NATIONAL MINORITIES;128
9.11.5;V. TYPES OF LEUKAEMIAS;128
9.11.6;VI. OCCUPATION;129
9.11.7;REFERENCES;129
9.11.8;EDITORS' NOTE;130
9.11.9;REFERENCES;130
9.12;CHAPTER 21. EPIDEMIOLOGIC AND IMMUNOLOGIC CHARACTERISTICS OF ACUTE LYMPHOBLASTIC LEUKAEMIA AND ADULT T-CELL LEUKAEMIA IN JAPAN;131
9.12.1;REFERENCES;133
9.13;CHAPTER 22. LEUKAEMIA AND LYMPHOMA IN MALAYSIA;138
9.13.1;METHODS;138
9.13.2;RESULTS;138
9.13.3;DISCUSSION;139
9.14;CHAPTER 23. SURFACE MARKER ANALYSIS OF ACUTE LYMPHOCYTIC LEUKAEMIA IN TAIWAN, REPUBLIC OF CHINA*;141
9.14.1;INTRODUCTION;141
9.14.2;PATIENTS AND METHODS;141
9.14.3;RESULTS;142
9.14.4;DISCUSSION;143
9.14.5;REFERENCES;145
9.15;CHAPTER 24. LEUKAEMIAS AND LYMPHOMAS AT LUCKNOW, INDIA;147
9.15.1;LYMPHOMAS;147
9.15.2;LEUKAEMIAS;148
9.15.3;REFERENCES;150
9.16;CHAPTER 25. LEUKAEMIA/LYMPHOMA INCIDENCE IN NEW ZEALAND: ACUTE LEUKAEMIA SUBTYPES IN THE SOUTH ISLAND OF NEW ZEALAND, 1983–1984;151
9.16.1;INCIDENCE OF LEUKAEMIA/LYMPHOMA IN NEW ZEALAND;151
9.16.2;ACUTE LEUKAEMIA SUBTYPES, SOUTH ISLAND, NEW ZEALAND 1983-1984;151
9.16.3;ADDENDUM;155
9.17;CHAPTER 26. CELL MARKERS AND ACUTE LEUKAEMIA SUBTYPES IN CHILE;156
9.17.1;INTRODUCTION;156
9.17.2;PATIENTS AND METHODS;156
9.17.3;RESULTS;156
9.17.4;DISCUSSION;158
9.17.5;REFERENCES;159
9.18;CHAPTER 27. IMMUNOLOGICAL PHENOTYPE OF LEUKAEMIAS AND LYMPHOMAS IN ARGENTINA;160
9.18.1;OVERALL INCIDENCE OF LEUKAEMIAS AND LYMPHOMA IN ARGENTINA;160
9.18.2;IMMUNOLOGICAL TYPING OF ACUTE LEUKAEMIA PERIOD MARCH/83- FEBRUARY/84;161
9.18.3;REFERENCES;163
9.19;CHAPTER 28. VARIATION BY RACE IN PRESENTING CLINICAL AND BIOLOGIC FEATURES OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA: IMPLICATIONS FOR TREATMENT OUTCOME*;164
9.19.1;INTRODUCTION;164
9.19.2;MATERIALS AND METHODS;164
9.19.3;RESULTS AND DISCUSSION;165
9.19.4;REFERENCES;169
10;PART IV: TECHNICAL APPENDIX;172
10.1;CHAPTER 29. PRACTICAL PROBLEMS IN STANDARDISED IMMUNOPHENOTYPING OF LEUKAEMIAS AND LYMPHOMAS;174
10.2;CHAPTER 30. IMMUNO-ALKALINE PHOSPHATASE LABELLING OF HAEMATOLOGICAL SAMPLES : TECHNIQUE AND APPLICATIONS;175
10.2.1;INTRODUCTION;175
10.2.2;THE IMMUNO-ALKALINE PHOSPHATASE METHOD;175
10.2.3;PRACTICAL ASPECTS OF APAAP CELL SMEAR STAINING;175
10.2.4;APPLICATIONS OF APAAP METHODS;175
10.2.5;REFERENCES;176
10.3;CHAPTER 31. DETECTION OF SURFACE MEMBRANE ANTIGENS BY A ROSETTE ASSAY USING ANTIBODY COUPLED RED CELLS;177
10.3.1;INTRODUCTION;177
10.3.2;METHODS;177
10.3.3;RESULTS AND DISCUSSION;177
10.3.4;REFERENCES;178