Griffiths Metabolomics, Metabonomics and Metabolite Profiling

1. Auflage 2007
ISBN: 978-1-84755-810-7
Verlag: Royal Society of Chemistry
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 336 Seiten, Web PDF

Reihe: RSC Biomolecular Sciences

The completion of gene sequencing has resulted in an intensified investigation of the proteome and metabolome. Metabolite profiling methods used for disease diagnosis have been expanded with the advent of new technology and are being applied extensively in the quest for the discovery of new markers for diseases. In this comprehensive resource, the Editor draws together experts from the field and provides an insightful introduction into the technology and methodology. Metabolomics, Metabonomics And Metabolite Profiling covers a broad range of topics including: * Mass spectrometry and NMR in metabolite profiling * Current applications of metabolite profiling for disease diagnosis * Studies of specific metabolite classes * Plant metabolites * Metabolite data mining * Global systems biology This book is a must have, up-to-date, reference which will appeal to academics, students, technicians and professionals working in, or joining this field.

Autoren/Hrsg.

Griffiths, William J

Weitere Mitwirkende

Lilley, David M J

Clore, Marius

Campbell, Simon

Neidle, Stephen

Wang, Yuqin

Ludwig, Christian

Gunther, Ulrich L

Han, Xianlin

Postle, Tony

Murphy, Robert

Clench, Malcolm

Thomas-Oates, Jane

Viant, Mark

Wilson, Ian D

Gross, Richard

Moritz, Thomas

Fahy, Eoin

Antonio, Carlo

Robinson, Sarah

Rodrigues, Joao

Fitzgerald, Mark

Barkley, Robert M

Earnshaw, Caroline J

Atkinson, Sally J

Burrell, Michael

Johansson, Annika I

Nordstrom, Anders

Nicholson, Jeremy K

Fachgebiete

• Naturwissenschaften Chemie Analytische Chemie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Inhaltsverzeichnis

1. Mass Spectrometry for Metabolite Identification; 2. 1D and 2D NMR Spectroscopy: from Metabolic Fingerprinting to Profiling; 3. Steroids, Sterols and the Nervous System; 4. Phospholipid Profiling; 5. New Developments in Multi-dimensional Mass Spectrometry-Based Shotgun Lipidomics; 6. Neutral Lipidomics and Mass Spectrometry; 7. Bioinformatics of Lipids; 8. Mass Spectrometry in Glycobiology, JoÒo Rodrigues; 9. Matrix Assisted Laser Desorption Ionisation Mass Spectrometric Imaging - Principles and Applications; 10. Plant Metabolomics; 11. Data Mining for Metabolomics; 12. Metabonomics and Global Systems Biology;

Über Autor(innen)

Murphy, Robert
Robert C Murphy graduated from Massachusetts Institute of Technology with a PhD in chemistry and he is currently a University Distinguished Professor at the University of Colorado. He has worked in the area of mass spectrometry and eicosanoid biochemistry for approximately 40 years with much of his research activities centered on the use of mass spectrometry to studies of arachidonic acid biochemistry and formation of the biologically active leukotriene mediators. His interests also include the structural characterizaton of bioactive lipid products derived from the reaction of reactive oxygen species with cellular lipids. Over 400 peer-reviewed papers in scientific journals and several books concerning mass spectrometry of lipids have been authored by him.