Harris Advances in Human Genetics

Erscheinungsjahr 2012
ISBN: 978-1-4615-8267-0
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 8, 445 Seiten, eBook

Reihe: Advances in Human Genetics

Zielgruppe

Research

Autoren/Hrsg.

Harris, Harry

Inhaltsverzeichnis

1 Genetics and Etiology of Human Cancer.- Introduction: The Etiology of Human Cancer.- Genetic States Associated with Cancer.- Survey of Human Cancers.- Mutation and Human Cancer.- Summary.- References.- 2 Population Genetics Theory in Relation to the Neutralist-Selectionist Controversy.- Deterministic One-Locus Theory.- Stochastic One-Locus Theory.- Two Loci.- Many Loci.- Models of Neutral Variation.- Mathematical Arguments Leading to the Non-Darwinian Theory.- Tests of the Neutral Theory Using Gene Frequency Data...- Tests Depending on Geographic Subdivision.- Informal Tests.- Tests Based on Phylogenetic Trees.- Conclusion.- References.- 3 The Human ?-Amylases.- Sources and Methods of Analysis.- Genetics of the Amylase Loci.- Biochemical Characterization.- Clinical Applications of Amylase Variation.- Speculations, Relevance, and Conclusions.- References.- 4 The Genetic Aspects of Facial Abnormalities.- Embryology of the Facial Structures.- Teratology.- Selected Overview of the More Common Genetic Facial Syndromes.- Genetic Counseling.- References.- 5 Some Facts and Fancies Relating to Chromosome Structure in Man.- Chromosome Composition and Fine Structure.- Not-So-Fine Structure: Chromosome Banding.- Repetitive Sequence DNAs in Human Chromosomes.- DNA Replication and the Lateral Differentiation of the Chromosome.- References.