Organic Syntheses Based on Name Reactions

4. Auflage 2025
ISBN: 978-0-08-102961-9
Verlag: Elsevier Inc

Buch, Englisch, 750 Seiten, Format (B × H): 216 mm x 279 mm, Gewicht: 1744 g

Organic Syntheses Based on Name Reactions is an invaluable reference book for organic chemists in academia and industry. In continuation of Hassner and Namboothiri’s popular 3rd Edition, this new edition with full colored graphics covers nearly 800 reactions, with numerous chemo-, regio- and stereoselective reactions. A diligently prepared summary of important information for each entry allows a chemist to grasp and apply these seminal reactions in their studies and research work. A general scheme, a brief introduction and a representative reaction from the literature with mechanistic outline, a brief procedure, and selected literature references to assist further reading are included in each entry. Besides various indexes (name, reagent, reaction and functional group transformation), a unique overview (in alphabetic order and in terms of reaction category) enable readers to look through the vast repertoire of key organic reactions and an appendix enriched with general information that is extremely useful to students and organic chemistry practitioners are part of this book. Additionally, an online companion site offers preface to previous editions and extensive reference materials. This new edition is very special with its exhaustive coverage, excellent organization and high-quality presentation and is an indispensable resource for every organic chemist.

Zielgruppe

Researchers in academia, industry and government laboratories as well as advanced undergraduate and graduate students working in organic synthesis, reactions and reagents, organometallic chemistry, and catalysis

Autoren/Hrsg.

Hassner, Alfred

Golan, Meir

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Medizinische Biotechnologie
• Naturwissenschaften Chemie Organische Chemie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie

Inhaltsverzeichnis

Forewords by David Milstein, Weizmann Institute of Science, Israel and Samir Z. Zard,
Ecole Polytechnique, France
Preface
An Overview of Synthesis-Related Name Reactions
Name Reactions A-Z
Greek Alphabet
Functional Groups
Important Organic Ring Systems
Common Protecting Groups (Implementation and Removal
List of Important Solvents Used in Organic Synthesis
The 20 Common Amino Acids
List of Abbreviations
Names Index
Reagents Index
Reactions Index
Functional Group Transformation Index

Über Autor(innen)

Golan, Meir
Meir was born in Israel in 1990. In 2008, he was recruited to the IDF and he served as a technological officer in ordnance units. After 5 years of service, he started his academic career in chemistry at Bar-Ilan University, Israel. He completed BSc in chemistry in 2018 and then continued to master degree course in chemistry in Prof David Zitoun lab in the Institute of Nanotechnology and Advanced Materials (Bar-Ilan University) where he specialized in the chemistry of Li-ion rechargeable batteries. Meir successfully graduated with his MSc degree in 2019. In the same year (at the start of the corona pandemic), he decided to shift his career to industry and worked as an organic chemist in Sigma-Aldrich (Merck) in Jerusalem where he was responsible for the synthesis of many challenging small organic compounds including steroids, dye materials, and drugs. Later he moved to work in an Israeli pharma company which focused on smart delivery of drugs to target organs using a unique technology. Subsequently (2022), he joined as a senior R&D chemist at My Polymer Ltd (Israel), a world leading manufacturer of low refractive index polymers and adhesives for the electro-optics and microelectronic Industry. Currently (2024), he works as a chemistry & biology account manager at Merck Israel. He visits hundreds of Israeli customers from academia and governmental research labs on a daily basis, and advise them on products and technologies for the benefit of their research and applications.

Hassner, Alfred
Alfred Hassner was born in 1930. He survived the holocaust as a young child. After WW II, he enrolled to the Technische Hochschule in Vienna (1949-1951), and then received his BSc from the University of Nebraska (1952). He obtained his PhD under Norman Cromwell at the University of Nebraska (1956) and then was a postdoc with Louis Fieser at Harvard University. He joined the University of Colorado at Boulder (1957) and became a Full Professor at the age of 36 (1966). In 1975, he moved to SUNY at Binghamton and in 1983 he joined Bar-Ilan University in Israel, where he was professor and after retirement Professor Emeritus, until his sad demise recently (2024) at the age of 94.

Hassner mentored over 50 graduate students and more than 60 postdocs, published more than 320 research articles and 14 books and monographs, and has had a major impact on chemical science for the last 7 decades.

Some of his most known contributions include the stereoselective introduction of nitrogen functionalities into organic molecules, the synthesis of steroidal heterocycles and other biologically active targets. He was one of the first to recognize the application of NMR half-widths to stereochemical structure assignments before high resolution NMR became available. Many useful reagents and concepts in organic synthesis are registered to his name. For example, he first proposed the concept of regiochemistry and regioselectivity, now universally used terminologies in organic chemistry.

As a world-renowned expert in organic synthesis, he has held visiting professorships and appointments in many universities worldwide and also served as a valuable consultant for many industrial companies around the world.
Hassner served as the president of the Israel Chemical Society - ICS (1991-1994). In 2007, he received the ICS prize for Excellence. In 2016, he received Honorary membership award for his lifetime achievement and outstanding contributions.