Organic Syntheses Based on Name Reactions

A Practical Guide to Over 800 Transformations
3. Auflage 2011
ISBN: 978-0-08-096630-4
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm, Gewicht: 1090 g

Organic Syntheses Based on Named Reactions is an indispensable reference companion for chemistry students and researchers. Building on Hassner & Stumer’s highly regarded 2e, this new work reviews 750 reactions, with over 100 new stereoselective and regioselective reactions. Each A-Z entry provides a carefully condensed summary of valuable information that a chemist needs to understand and utilize these fundamental reactions in their work, including brief practical details. The book is illustrated with real synthetic examples from the literature and about 3,400 references to the primary literature to aid further reading. Extensive indexes (name, reagent, reaction) and a very useful functional group transformation index help the reader fully navigate this extensive collection of important reactions. With its comprehensive coverage, superb organization and quality of presentation, this long-awaited new edition belongs on the shelf of every organic chemist.

Zielgruppe

<p>For researchers and advanced chemistry students in academia and in chemical, pharmaceutical and biotechnology industries.</p>

Autoren/Hrsg.

Hassner, Alfred

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Medizinische Biotechnologie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Naturwissenschaften Chemie Organische Chemie

Inhaltsverzeichnis

Rearrangement
Reaction
Aromatic Tritylation
Ketone Oxidation
Arylpyridine synthesis
N-Heterocycle Amination
Indolizine Synthesis
Cyclohexene Synthesis
Reaction Asymmetric
Methylenation Reagent
Alkylation Acylation
Carbonylation
Reagents
Bromination
Grignard Reagent
Asymmetric Epoxidation
Allylation
Ce Reducing Agent
Aminomethylation
Addition
C-C Cross Coupling
Oxidation
Cyclopentenone
Annulation
Chromone
Quinoline
Oxazole
Asymmetric Epoxidation
C-C Coupling
Allylation; UGI Multicomponent Condensation
Reagent
Olefin Synthesis
Lactonization
Cyclohexadienone Synthesis

Über Autor(innen)

Hassner, Alfred
Alfred Hassner was born in 1930. He survived the holocaust as a young child. After WW II, he enrolled to the Technische Hochschule in Vienna (1949-1951), and then received his BSc from the University of Nebraska (1952). He obtained his PhD under Norman Cromwell at the University of Nebraska (1956) and then was a postdoc with Louis Fieser at Harvard University. He joined the University of Colorado at Boulder (1957) and became a Full Professor at the age of 36 (1966). In 1975, he moved to SUNY at Binghamton and in 1983 he joined Bar-Ilan University in Israel, where he was professor and after retirement Professor Emeritus, until his sad demise recently (2024) at the age of 94.

Hassner mentored over 50 graduate students and more than 60 postdocs, published more than 320 research articles and 14 books and monographs, and has had a major impact on chemical science for the last 7 decades.

Some of his most known contributions include the stereoselective introduction of nitrogen functionalities into organic molecules, the synthesis of steroidal heterocycles and other biologically active targets. He was one of the first to recognize the application of NMR half-widths to stereochemical structure assignments before high resolution NMR became available. Many useful reagents and concepts in organic synthesis are registered to his name. For example, he first proposed the concept of regiochemistry and regioselectivity, now universally used terminologies in organic chemistry.

As a world-renowned expert in organic synthesis, he has held visiting professorships and appointments in many universities worldwide and also served as a valuable consultant for many industrial companies around the world.
Hassner served as the president of the Israel Chemical Society - ICS (1991-1994). In 2007, he received the ICS prize for Excellence. In 2016, he received Honorary membership award for his lifetime achievement and outstanding contributions.