E-Book, Englisch, Band 945, 535 Seiten, eBook
E-Book, Englisch, Band 945, 535 Seiten, eBook
Reihe: Advances in Experimental Medicine and Biology
ISBN: 978-3-319-43624-1
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: Kein
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
Mechanisms and biological roles of DNA methylation and DNA methyltransferases – from past achievements to future challenges.- DNA and RNA pyrimidine nucleobase alkylation at the carbon-5 position.- Bacterial DNA methylation and methylomes.- Domain structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA methyltransferases.- Enzymology of mammalian DNA methyltransferases.- Genetic studies on mammalian DNA methyltransferases.- The role of DNA methylation in cancer.- Structure and mechanism of plant DNA methyltransferases.- DNA methylation and gene regulation in honey bees: from genome-wide analyses to obligatory epi-alleles.- N6-methyladenine: a conserved and dynamic DNA mark.- Pathways of DNA demethylation.- Structure and function of TET enzymes.- Proteins that read DNA methylation.- DNA base flipping – a general mechanism for writing, reading, and erasing DNA modifications.- Current and emerging technologies for the analysis of the genome-wide and locus-specific DNA methylation patterns.- DNA methyltransferase inhibitors – development and applications.- Rewriting DNA methylation signatures at will: the curable genome within reach?.- Engineering and directed evolution of DNA methyltransferases.- DNA labeling using DNA methyltransferases.