Jonkman Autoimmune Bullous Diseases

Text and Review
1. Auflage 2016
ISBN: 978-3-319-23754-1
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 215 Seiten

Reihe: Medicine

This book provides obligatory study material on courses on autoimmune bullous diseases. Residents and researchers in dermatology and adjacent disciplines can use the book as a quick reference guide when dealing with these patients. The book contains protocols and follows international guidelines.

Currently there is no quick primer on Autoimmune Bullous Diseases for dermatologists who wish to learn the subtleties of diagnosis and management of this group of mucocutaneous diseases.

Since mucous membranes are also included the following medical disciplines might be interested too: oral medicine and stomatology, ENT, ophthalmology, gynaecology, gastro-enterology.

The Center for Blistering Diseases in Groningen has organized since the year 2000 an annual course on Bullous Diseases for dermatologists and pathologists. The staff is selected from the faculty. The course is interactive and problem-oriented. The proposed book would represent the documented practical knowledge of the staffon these diseases. The information should be clear and practical with examples and questions for self-assessment.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Jonkman, Marcel F.

Inhaltsverzeichnis

Part I: Immunology and diagnostic
tests-B-cells,
autoantibodies and isotypes.- Dermatological examination of bullous diseases.- How
to take a biopsy.- Direct
immunofluorescence.-
Indirect immunofluorescence.- Immunoblot.- ELISA
testing.- Part II: Pemphigus-Structure of desmosomes.- Pemphigus foliaceus.- Pemphigus vulgaris.- Paraneoplastic pemphigus.- IgA pemphigus.- Part III: Pemphigoids-Structure of hemidesmosomes and basement
membrane zone.- Cutaneous
pemphigoid.- Mucous membrane pemphigoid.- Epidermolysis bullosa acquisita.- Bullous systemic lupus
erythematosus.- Linear IgA
Disease.- Part IV: Other
inflammatory bullous diseases-Dermatitis
herpetiformis.- Erythema multiforme.- Porphyria and pseudoporphyria.- Bullous dermatitis artefacta.- Part V:
Resources-Patient support
groups.- International centres for AIBD.

Über Autor(innen)

Marcel F. Jonkman is professor and chair of the department of Dermatology at the University Medical Center Groningen (UMCG). Since 1992 he runs the Center for Blistering Diseases at the University, which is the only expertise center for autoimmune bullous diseases, epidermolysis bullosa, and other skin fragility disorders in the Netherlands. The center has its own laboratory for research and  immunodiagnosis of blistering diseases. It provides weekly clinical services for patients with blistering diseases. Hundreds of patients with an autoimmune bullous disease from all over the country (16.920.510 inhabitants, 2015) have visited the center in all these years. 

The textbook is the effort of the senior staff and PhD’s in Groningen who wrote this ‘all-Groningen book’. The senior staff has gained years of experience in diagnosis and management of autoimmune bullous diseases, and reported their scientific findings in many publications. The annual Course on Blister Diseases in Groningen, that runs since the year 2000, provided much of the didactic structure used in this book. The photographers Siep Noorman and PietToonder signed for the excellent medical photographs that were selected from a digital image database with more than 250,000 images of dermatological disease.