Laskowitz / Grant Translational Research in Traumatic Brain Injury

Erscheinungsjahr 2015
ISBN: 978-1-4665-8492-1
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 436 Seiten

Reihe: Frontiers in Neuroscience

Translational Research in Traumatic Brain Injury is designed to address the key issues in the epidemiology, basic science, and treatment of traumatic brain injury (TBI). Edited by two clinically active physician scientists, the book presents contributions from faculty who are international leaders in the areas of molecular biology, translational modeling, treatment, and rehabilitation of traumatic brain injury.

The book covers a wide scope of TBI research critically important to the neurobiology research community, clinicians involved in the care of TBI patients, as well as industry leaders interested in developing new therapies for acute brain injury. It examines the full spectrum of TBI events, from mild sports-related injuries to severe blast injuries. It discusses fundamental cell mechanisms and pathophysiology, as well as animal modeling, clinical diagnosis, current therapeutic strategies, and future treatments. The book also describes long-term neuropsychiatric symptoms and the relationship of TBI to the development of post-concussive syndrome and post-traumatic stress disorder.

Autoren/Hrsg.

Laskowitz, Daniel

Grant, Gerald

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft

Inhaltsverzeichnis

Epidemiology

Epidemiology

Sports Injury

Pathophysiology

Diffuse Axonal Injury

BBB Breakdown

Cellular

Neuroplasticity after TBI

Neuroinflammation

Neurosteroids

Genetics of TBI

Acute Neuronal Excitability and Seizures after TBI

Animal Models

Diagnosis of TBI

Biomarkers

Radiology

Current Treatment and Sequelae

Current Therapeutic Strategies

Epilepsy after TBI

Neurocognitive Sequelae and Relationship to PTSD

Management and Monitoring of Cerebral Physiology and ICP

Clinical Trials and Future Therapies

Clinical Trials in TBI

Clinical Trials in PTSD

Cell-based Therapies in TBI

Neurostimulation

Machine/Brain Interface