1. Auflage 2005,
528 Seiten, Gebunden, Format (B × H): 152 mm x 229 mm, Gewicht: 816 g
Reihe: Chromatographic Science Series
Verlag: Taylor & Francis Inc
Li Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and DiscoveryThe microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced, and processes seamlessly integrated. This microscale advantage translates into greater sensitivity, more accurate results, and better information. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery focuses on all aspects of the microfluidic lab-on-a-chip technologies and offers an overview of the available technology, its limitations, and its breakthroughs over the years. It emphasizes analytical applications of microfluidic technology and offers in-depth coverage of micromachining methods, microfluidic operations, chemical separations, sample preparation and injection methods, detection technology, and various chemical and biological analyses. Other topics of interest include the use of polymeric chips, fluid flow valve and control, single-cell analysis, DNA and RNA amplification techniques, DNA hybridization, immunoassays and enzymatic assays.Originally conceived as a single chapter published in Ewing's Analytical Instrumentation, this book is a gateway to the vast literature and conference proceedings on the topic. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery expands upon its roots to present a comprehensive treatment of microfluidic lab-on-a-chip methods and applications for novices and advanced researchers alike.
Chemical engineers, biolomedical researchers, and materials scientists.
Weitere Infos & Material
Introduction Micromachining MethodsMicromachining of Silicon Micromachining of Glass Micromachining of Fused Quartz (or Fused Silica) Micromachining of Polymeric ChipsMetal Patterning World-to-Chip Interface Microfluidic FlowLiquid Pumping Methods Microfluidic Flow Control Sample IntroductionElectrokinetic Injection Hydrodynamic Injection Other Sample Injection Methods Sample Pre-concentrationSample Stacking Extraction Porous Membrane Other Pre-concentration Methods SeparationGas Chromatography (GC) Capillary Electrophoresis (CE) Chromatographic Separations Coupled Separations Detection MethodsOptical Detection Methods Electrochemical (EC) Detection Mass Spectrometry (MS) Other Detection Methods Applications to Cellular/Particle AnalysisRetention of Cells and Particles Studies of Cells in a Flow Other Cell Operations Applications to Nucleic Acids AnalysisNucleic Acids Extraction and Purification Nucleic Acids Amplification DNA Hybridization Other Nucleic Acid Applications Applications to Protein AnalysisImmunoassay Protein Separation Enzymatic AssaysAppendix Problem Sets Introduction Micromachining Microfluidic Flow Sample Introduction Sample Preconcentration Separation Detection Cellular Analysis Nucleic Acid Analysis Protein Analysis References Glossary