Liu Handbook of Listeria Monocytogenes

Erscheinungsjahr 2008
ISBN: 978-1-4200-5141-4
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 552 Seiten

Once feared as a deadly intracellular bacterium with the extraordinary capacity to survive a wide array of arduous external stressors, Listeria monocytogenes is increasingly recognized as a preferred vector for delivering anti-infective and anti-cancer vaccine molecules.

A reliable, single-source reference on the fundamental aspects of this bacterium is crucial to support future study and further the advancement of biomedical sciences and intervention strategies.

Drawn from an international panel of scientists with notable expertise in their respective fields, the Handbook of Listeria monocytogenes is divided into four sections:

Section I discusses the biology and pathogenicity of this bacterium, including epidemiology and stress responses.

Section II demonstrates identification and detection techniques such as phenotypic and genotypic identification, strain typing, and virulence determination.

Section III details the current knowledge of genetic manipulation of Listeria, including comparative genomics, genomic divisions, epidemic clones and population structure, and analysis of cell envelope proteins.

Section IV covers innate and adaptive immunity against Listeria, and examines the use of this bacterium for anti-infective and anti-cancer vaccine development.

The first comprehensive compilation of knowledge in this area, this handbook is an indispensable reference for anyone embarking on the path of manipulation of Listeria as either a model for the study of the host-bacterium relationship or as a tool for delivering protective molecules to cytoplasm.

Zielgruppe

Microbiologists and clinical laboratory scientists.

Autoren/Hrsg.

Liu, Dongyou

Fachgebiete

• Naturwissenschaften Biowissenschaften Bakteriologie

Inhaltsverzeichnis

BIOLOGY AND PATHOGENICITY

Biology, M. Wagner and J. McLaughlin

Epidemiology, D. Liu

Stress Responses, H.M. Stack, C.G.M. Gahan, and C. Hill

Pathogenesis, M. Kuhn, M.M. Scortti, and J.A. Vázquez-Boland

IDENTIFICATION AND DETECTION

Phenotypic Identification, L. Gorski

Genotypic Identification, D. Liu, M.L. Lawrence, A.J. Ainsworth, and F.W. Austin

Strain Typing, Y. Chen and S.J. Knabel

Virulence Determination, S.M. Roche, P. Velge, and D. Liu

GENOMICS AND PROTEOMICS

Genetic Manipulations, A. Bigot and A. Charbit

Comparative Genomics and Evolution of Virulence, S. Barbuddhe, T. Hain, and T. Chakraborty

Genomic Divisions, Epidemic Clones and Population Structure, Y. Cheng, R.M. Siletzky, and S. Kathariou

Analysis of Cell Envelope Proteins, M. Hébraud and M. Desvaux

IMMUNITY AND VACCINES

Innate Immunity, G. Geginat and S. Grauling-Halama

Adaptive Immunity, M. Mitsuyama

Anti-Infective Vaccine Strategies, T. Nagata and Y. Koide

Anti-Cancer Vaccine Strategies, M.M. Seavey, T. Verch, and Y. Paterson