Makarov Single Molecule Science

Physical Principles and Models
Erscheinungsjahr 2015
ISBN: 978-1-4665-5952-3
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 214 Seiten

The observation and manipulation of individual molecules is one of the most exciting developments in modern molecular science, and the utility of single-molecule methods has proven invaluable in such fields as nanoscience and molecular biology. This book provides a general framework necessary for understanding single-molecule phenomena. It introduces the relevant basic mathematical and physical concepts, and then discusses various approaches to the problem of interpreting single-molecule data. It thoroughly explains the physical principles underlying the major classes of single-molecule experiments, such as fluorescence measurements, force-probe spectroscopy, and nanopore experiments.

Autoren/Hrsg.

Makarov, Dmitrii E.

Fachgebiete

• Naturwissenschaften Chemie Physikalische Chemie
• Naturwissenschaften Physik Quantenphysik Kernphysik
• Technische Wissenschaften Technik Allgemein Nanotechnologie
• Technische Wissenschaften Maschinenbau | Werkstoffkunde Maschinenbau Mechatronik, Mikrosysteme (MEMS), Nanosysteme

Inhaltsverzeichnis

History of single-molecule chemistry and physics: From the ancient Mayans to quantum interferometers

How the properties of individual molecules are measured

Single-molecule versus traditional view of chemical kinetics

How molecules explore their energy landscapes

Microscopic view of the rate of a chemical reaction: The single-molecule perspective

Molecular transition paths: Why going uphill may be faster

Properties of light emitted by a single molecule

Solving the inverse problem: learning about molecular trajectories by watching individual photons

Single-molecule electronics

Single molecules pushed, pulled, and squeezed by mechanical forces

Nonequilibrium thermodynamics of single molecules: The Jarzynski identity and fluctuation theorems

Nature doing single-molecules: Single-molecule biology

Appendix A: Introduction to probability theory

Appendix B: Properties of simple random walks

Appendix C: Elements of statistical mechanics

Appendix D: Elements of quantum mechanics