E-Book, Englisch, 488 Seiten
Morishita / Park Biodrug Delivery Systems
1. Auflage 2013
ISBN: 978-1-4200-8671-3
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
Fundamentals, Applications and Clinical Development
E-Book, Englisch, 488 Seiten
Reihe: Drugs and the Pharmaceutical Sciences
ISBN: 978-1-4200-8671-3
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
An international group of leading experts in drug development and biopharmaceutical science discusses the latest advances in biodrug delivery systems and associated techniques.
Components of successful formulation, delivery, and production of biodrugs, are explored, including:
- sophisticated plants and complex processes
- a well-trained and knowledgeable staff
- proper quality control
In addition, Biodrug Delivery Systems examines:
- ADME (Absorption, Metabolism, Distribution, and Elimination of biodrugs)
- directing and influencing the successful development of currently marketed best-selling biodrugs
- routes of administration
- mechanisms of biodrug absorption
- alternative possibilities for drug delivery routes
- a focus on formulations on the market from the perspective of industry personnel involved in biodrug development
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
1. Overview of Biodrug delivery system. 2. Issues in Biodrug delivery system. 3. Pharmacokinetic consideration of Biodrugs. Specific Route of Delivery. 1. Parenteral delivery. 2. Brain delivery. 3. Ocular delivery. 4. Nasal delivery. 5. Buccal delivery. 6. Pulmonary delivery. 7. Transdermal delivery. 8. Colon delivery. 9. Oral delivery. 10. Cellular delivery. Delivery Systems. 1. Targeting: PK consideration. Monoclonal antibody. Receptor-mediated endocytosis. 2. Bioadhesive delivery system. 3. Modified release delivery system. 4. Nanoparticulate delivery system. 5. Lipid-based delivery system. 6. Implantable delivery system. 7. Modifying the physiochemical nature of Biodrugs. 8. Regulatory perspective of Biodrug development. Development of Biodrug Products. 1. Leuplin. 2. ANP (atrial natriuretic peptide). 3. Amylin and GLP-1 agonists. 4. GHRP-2 (growth hormone releasing peptide. 5. Endothelin receptor antagonist. 6. Angiotensin II receptor antagonist. 7. Insulin (inhalation). 8. Calcitonin (nasal, etc.). 9. Sandstatin LAR. 10. Interferon. 11. Vaccine. Perspective of Biodrug Products.
