Newman Biostatistical Methods in Epidemiology

1. Auflage 2003
ISBN: 978-0-471-46160-9
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 408 Seiten, E-Book

Reihe: Wiley Series in Probability and Statistics

An introduction to classical biostatistical methods inepidemiology
Biostatistical Methods in Epidemiology provides anintroduction to a wide range of methods used to analyzeepidemiologic data, with a focus on nonregression techniques. Thetext includes an extensive discussion of measurement issues inepidemiology, especially confounding. Maximum likelihood,Mantel-Haenszel, and weighted least squares methods are presentedfor the analysis of closed cohort and case-control data.Kaplan-Meier and Poisson methods are described for the analysis ofcensored survival data. A justification for using odds ratiomethods in case-control studies is provided. Standardization ofrates is discussed and the construction of ordinary, multipledecrement and cause-deleted life tables is outlined. Sample sizeformulas are given for a range of epidemiologic study designs. Thetext ends with a brief overview of logistic and Cox regression.Other highlights include:
* Many worked examples based on actual data
* Discussion of exact methods
* Recommendations for preferred methods
* Extensive appendices and references
Biostatistical Methods in Epidemiology provides anexcellent introduction to the subject for students, while alsoserving as a comprehensive reference for epidemiologists and otherhealth professionals.
For more information, visit www.wiley.com/mathematics

Autoren/Hrsg.

Newman, Stephen C.

Inhaltsverzeichnis

Introduction.
Measurement Issues in Epidemiology.
Binomial Methods for Single Sample Closed Cohort Data.
Odds Ratio Methods for Unstratified Closed Cohort Data.
Odds Ratio Methods for Stratified Closed Cohort Data.
Risk Ratio Methods for Closed Cohort Data.
Risk Difference Methods for Closed Cohort Data.
Survival Analysis.
Kaplan-Meier and Actuarial Methods for Censored SurvivalData.
Poisson Methods for Censored Survival Data.
Odds Ratio Methods for Case-Control Data.
Standardized Rates and Age-Period-Cohort Analysis.
Life Tables.
Sample Size and Power.
Logistic Regression and Cox Regression.
Appendix A: Odds Ratio Inequality.
Appendix B: Maximum Likelihood Theory.
Appendix C: Hypergeometric and Conditional PoissonDistributions.
Appendix D: Quadratic Equation for the Odds Ratio.
Appendix E: Matrix Identities and Inequalities.
Appendix F: Survival Analysis and Life Tables.
Appendix G: Confounding in Open Cohort and Case-ControlStudies.
Appendix H: Odds Ratio Estimate in a Matched Case-ControlStudy.
References.
Index.

Über Autor(innen)

STEPHEN C. NEWMAN, MD, MSc, is Professor of Psychiatry at the University of Alberta, Canada.