Nuñez / Malmierca Corticofugal Modulation of Sensory Information

1. Auflage 2007
ISBN: 978-3-540-36771-0
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 187, 75 Seiten, eBook

Reihe: Advances in Anatomy, Embryology and Cell Biology

"Sensory signals reach the cerebral cortex after having made synapses in different relay stations along the sensory pathway. The flow of sensory information in subcortical relay stations is controlled by the action of precise topographic connections from the neocortex. Several lines of research indicate that the massive corticifugal system improves ongoing subcortical sensory processing and reorganizes the receptive fields in visual, auditory and somatosensory systems. In all these sensory systems cortical neurons mediate both the highly focused positive feedback to subcortical neurons with overlapping receptive fields and a widespread inhibition to ""non-matching neurons"". This cortical feedback, which has been called ""egocentric selection"", can play a pivotal role in gating the sensory information that reaches the thalamus and cortex. Thus, corticofugal projections may contribute to selective attention since they enhance neuronal responses for attentionally relevant stimuli and by suppressing sensory responses of distractive stimuli. Also, corticofugal projections enhance oscillatory activity in order to synchronize neurons located in the same or in different relay stations in order to improve sensory processing. In conclusion, corticofugal pathways precisely control sensory transmission throughout the central nervous system."

Zielgruppe

Research

Autoren/Hrsg.

Nuñez, A.

Malmierca, E.

Inhaltsverzeichnis

1 Introduction.- 2 Anatomical projections from sensory cortical areas to the thalamus.- 2.1 General characteristics of corticothalamic projections.- 2.2 Types of corticothalamic projections.- 2.3 Cells of origin for the corticothalamic projections.- 2.4 Neurotransmitter actions.- 2.5 Specific characteristics of corticothalamic projections to the sensory thalamus.- 3. Corticofugal projection to subthalamic relay stations.- 3.1 Auditory system.- 3.2 Visual system.- 3.3 Somatosensory system.- 4 Corticofugal modulations of sensory responses.- 4.1 Corticofugal modulation of auditory responses.- 4.2 Corticofugal modulation of visual responses.- 4.3 Somatosensory system.- 5 Functional considerations.- 5.1 Corticofugal modulation of sensory transmission. Egocentric selection.- 5.2 Corticofugal modulation of neuronal rhythmic activities and neuronal synchronization.- 5.3 Contribution of corticofugal projections in attentional filtering.- References.- Subject index.