O'Kelly / Ratitch Clinical Trials with Missing Data

A Guide for Practitioners
1. Auflage 2014
ISBN: 978-1-118-76250-9
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 472 Seiten, E-Book

Reihe: Statistics in Practice

This book provides practical guidance for statisticians,clinicians, and researchers involved in clinical trials in thebiopharmaceutical industry, medical and public healthorganisations. Academics and students needing an introduction tohandling missing data will also find this book invaluable.
The authors describe how missing data can affect the outcome andcredibility of a clinical trial, show by examples how a clinicalteam can work to prevent missing data, and present the reader withapproaches to address missing data effectively.
The book is illustrated throughout with realistic case studies andworked examples, and presents clear and concise guidelines toenable good planning for missing data. The authors show how tohandle missing data in a way that is transparent and easy tounderstand for clinicians, regulators and patients. Newdevelopments are presented to improve the choice and implementationof primary and sensitivity analyses for missing data. Many SAS codeexamples are included - the reader is given a toolbox forimplementing analyses under a variety of assumptions.

Autoren/Hrsg.

O'Kelly, Michael

Ratitch, Bohdana

Über Autor(innen)

MICHAEL O'KELLY, Senior Strategic BiostatisticsDirector, Quintiles Ireland Ltd, Ireland.
BOHDANA RATITCH, Senior Biostatistician, Quintiles,Montreal, Canada.