Parihar / Pradeep Mehta Lab-on-a-chip Devices for Advanced Biomedicines

Laboratory Scale Engineering to Clinical Ecosystem
1. Auflage 2024
ISBN: 978-1-83767-348-3
Verlag: Royal Society of Chemistry
Format: EPUB
Kopierschutz: 6 - ePub Watermark

E-Book, Englisch, 694 Seiten

The global miniature devices market is poised to surpass a valuation of $12–$15 billion USD by the year 2030. Lab-on-a-chip (LOC) devices are a vital component of this market.

Comprising a network of microchannels, electrical circuits, sensors, and electrodes, LOC is a miniaturized integrated device platform used to streamline day-to-day laboratory functions, run cost-effective clinical analyses and curb the need for centralized instrumentation facilities in remote areas. Compact design, portability, ease of operation, low sample volume, short reaction time, and parallel investigation stand as the pivotal factors driving the widespread acceptance of LOC within the biomedical community.

In this book, the Editors meticulously explore LOC through three key ‘Ts’:

- Theories (microfluidics, microarrays, instrumentation, software);
- Technologies (additive manufacturing, artificial intelligence, computational thinking, smart consumables, scale-up tactics, and biofouling); and

- Trends (biomedical analysis, point-of-care diagnostics, personalized healthcare, bioactive synthesis, disease diagnosis, and space applications)

This comprehensive text not only provides readers with a thorough understanding of the current advancements in the LOC domain but also offers valuable insights to support the utilization of miniaturized devices for enhanced healthcare practices. Aimed at career researchers looking for instruction in the topic and newcomers to the area, the book is also useful for undergraduate and postgraduate students embarking on new studies or for those interested in reading about the LOC platform.

Autoren/Hrsg.

Parihar, Arpana

Pradeep Mehta, Piyush

Fachgebiete

• Naturwissenschaften Chemie Analytische Chemie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie

Inhaltsverzeichnis

Lab-on-a-chip – Reform, Perform, and Transform;Lab-on-a-chip: A Road Map of Silicon Chemistry to Multipurpose Microfluidic Chips;Lab-on-a-chip – Fabrication and Frontiers Aiming at Biomedicines;Lab-on-a-chip – Summary of 3D/4D Printed Biochips;Lab-on-a-chip – A Novel Platform for Disease Diagnosis;Role of Microfluidics in Drug Encapsulation for Point of Care Diagnosis and Prognosis;Lab-on-a-chip – A Stepping Stone for Personalized Healthcare Management;Lab-on-a-chip for In-vitro Diagnosis: Manipulating the Power of Nanoparticles;Integration of Artificial Intelligence and Computational Thinking in Lab-on-a-chip Technology for Quality Improvement in Healthcare;Lab-on-a-chip – An Emerging Analytical Tool for Drug Testing;Lab-on-a-chip – Efficient Preparation of Bioactive Compounds Using On-chip Flow Synthesis;DIY Lab-on-a-chip Platforms: A Solution for Simple Nucleic Acid-based Assays in the Absence of Proper (Chip) Facilities;When Earth Is Not Enough – Lab-on-a-chip Accelerating Space Research;Lab-on-a-chip – Mechanism and Mitigation of Biofouling;Organ-on-a-chip Technology Roadmap: Regulatory Framework, Industry Adoption, Key Players, Technology Transfer, Validation, and Ethical Considerations;Lab-on-a-chip: From Prototyping to Scale-up Production;Lab-on-a-chip – Unit Operations to Scale Up Strategies;Miniaturized Devices – A Silk Route for Innovative Commercial Prospects