Pasternak The Opiate Receptors

2. Auflage 2011
ISBN: 978-1-60761-993-2
Verlag: Humana Press
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 516 Seiten

Reihe: Biomedical and Life Sciences

This new edition covers the latest knowledge on opiate receptors and related receptor subtypes. It discusses many topics pertaining to the unique integrated approach of correlating the biochemical, physiological and pharmacological aspects of opiate reaction.

Zielgruppe

Research

Autoren/Hrsg.

Pasternak, Gavril W.

Inhaltsverzeichnis

You’ve Come a Long Way Baby.- The evolution of concepts of opioid receptors.- Pharmacology of opioid drugs.- Opioid receptors: the early years.- Endogenous opioids.- Molecular biology of mu opioid receptors.- Delta Opioid Receptors.- Kappa opioid receptor gene and the regulatory mechanisms of its protein expression.- Opioid receptor signal transduction mechanisms.- Mu opioid receptor mediated analgesia and reward.- Kappa opioid receptor function.- Delta opioid receptor function.- Genetics of opioid receptor functions in mice.- Opioid receptor trafficking.- Opioid receptor dimerization.- Molecular modulation of in vivo tolerance.- Genetics of opioid actions.

Über Autor(innen)

In 1988, Gavril W. Pasternak published the first edition of The Opiate Receptors. Dr. Pasternak is affiliated with the Molecular Pharmacology & Chemistry department at the Sloan-Kettering Institute (Memorial Sloan-Kettering Cancer Center).