Pfaff / Kordon / Chanson Hormones and Social Behavior

1. Auflage 2008
ISBN: 978-3-540-79288-8
Verlag: Springer Berlin Heidelberg
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 199 Seiten

Reihe: Research and Perspectives in Endocrine Interactions

This book concentrates on two major topics: firstly, the molecular and neural biology of hormone actions relevant to normal social behaviors; and secondly, the clinical treatment of human patients in whom these behaviors have gone wrong.

Autoren/Hrsg.

Kordon, Claude

Chanson, Philippe

Christen, Yves

Pfaff, Donald W.

Inhaltsverzeichnis

1;Preface;5
1.1;Social Bonding, a Product of Evolution: an Introduction to the Volume;5
1.2;References;7
2;Table of Contents;9
3;List of Contributors;11
4;Modules, Minds and Morality;13
4.1;Summary;13
4.2;Human Faces: An Illustrative Example of Domain Specificity;14
4.3;The Ingredients of a Language Faculty;15
4.4;The Ingredients of a Moral Faculty;17
4.5;Folk Mental States;17
4.6;Emotional Processing;18
4.7;Moral Specificity;20
4.8;References;20
5;Brain Mechanisms Theoretically Underlying Extremes of Social Behaviors: The Best and the Worst;25
5.1;Summary;25
5.2;Introduction;25
5.3;Implications of Loss of Social Information in Cortical Circuits;25
5.4;CNS Arousal Mechanisms Leading to Social Anxiety Leading to Autism;27
5.5;Outlook;33
5.6;References;33
6;Serotonergic Modulation of Sex and Aggression;39
6.1;Summary;39
6.2;Introduction to the Serotonergic System and 5-HT Receptors;39
6.3;5-HT and Aggression: Is 5-HT Inhibitory in Aggression?;40
6.4;5-HT and Sexual Behavior;46
6.5;Are the Serotonergic Systems Involved in Aggressive and Sexual Behavior ( Dis) similar?;51
6.6;References;52
7;The Effect of Neuropeptides on Human Trust and Altruism: A Neuroeconomic Perspective;59
7.1;Summary;59
7.2;Neuroeconomic Tools for Studying Social Preferences and Trust;60
7.3;The Impact of Oxytocin on Human Trust;62
7.4;The Impact of OT on Generosity;63
7.5;The Impact of OT on Beliefs About the Trustees’ Trustworthiness;65
7.6;Does OT Reduce Betrayal Aversion?;65
7.7;Which Brain CircuitryMight Mediate OT’s Effect on Trust?;66
7.8;Concluding Remarks;66
7.9;References;67
8;Molecular Neurobiology of the Social Brain;69
8.1;Summary;69
8.2;Introduction;69
8.3;Oxytocin and Vasopressin: Social Neuropeptides;70
8.4;Neuropeptide Regulation of Social Bonding in Monogamous Rodents;70
8.5;Species Differences in Neuropeptide Receptor Distribution and Social Behavior;71
8.6;A NeuralModel of Social Bonding;72
8.7;Molecular Mechanisms Underlying Diversity in Social Behavior;73
8.8;Implications for Human Behavior;73
8.9;Conclusion;74
8.10;References;74
9;Impact of Brain Evolution on Hormones and Social Behaviour;77
9.1;Summary;77
9.2;Introduction;77
9.3;Olfaction and Social Reward;79
9.4;The Role ofMammalian Olfactory Systems in Social Bonding;81
9.5;Social Complexity, Neuropeptides and Brain Reward;83
9.6;Opioids and Primate Infant Attachment;84
9.7;Opioids and Maternal Bonding;84
9.8;Discussion;86
9.9;References;88
10;Brain OxytocinMediates Beneficial Consequences of Close Social Interactions: From Maternal Love and Sex;93
10.1;Summary;93
10.2;Introduction;94
10.3;Complex Adaptations of theMaternal Brain Peripartum;94
10.4;Activation of Brain OXT and PRL Systems Around Birth;95
10.5;Functions of Locally Released OXT and PRL in the Maternal Brain;95
10.6;Brain OXT andMaternal Aggression;96
10.7;Beneficial Consequences of Being a Mother;97
10.8;Mechanisms of Blunted Stress Responses Peripartum;98
10.9;OXT and PRLMediate the Beneficial Effects for the Mother;99
10.10;OXT Effects on Stress Coping in theMale Brain;100
10.11;Positive Effects of Social Interactions in the Male: Involvement of OXT?;100
10.12;Activation of OXT in the Male Brain During Social Stimuli: Effects of Sexual Activity;101
10.13;OXTMediates the Anxiolytic Effect of Sexual Activity in Males;102
10.14;OXTMediates the Rewarding Nature of Close Social Interactions: Maternal and Romantic Love;104
10.15;References;106
11;Hormones, Brain Plasticity and Reproductive Functions;115
11.1;Summary;115
11.2;Introduction;115
11.3;Morphological Plasticity of the OT System;117
11.4;Neuronal-glial Plasticity in Other Neuroendocrine Centers;119
11.5;Consequences of Neuronal-glial Plasticity at the Cellular Level;120
11.6;Consequences on Neuroendocrine Regulations;122
11.7;Cell Mechanisms Underlying Astro-neuronal Plasticity;124
11.8;References;127
12;Neuroendocrine Mechanisms Underlying the Intergenerational Transmission of Maternal Behavior and Infant Abuse in Rhesus Macaques;133
12.1;Summary;133
12.2;Introduction;133
12.3;Brain Serotonin and Naturally Occurring Variation in PrimateMaternal Behavior;134
12.4;Serotonin and Maternal Behavior;137
12.5;References;139
13;Brain Corticosteroid Receptor Function in Response to Psychosocial Stressors;143
13.1;Summary;143
13.2;Introduction;143
13.3;The Stress Response;144
13.4;The Principle of CORT Action and Receptors;146
13.5;Function in behavioral adaptation;147
13.6;Mechanism: Responsive Ggene Patterns and Pathways;152
13.7;Diabetes as a DiseaseModel for Aberrant CORT;154
13.8;Genetics and Early Experience;154
13.9;Perspectives;158
13.10;References;158
14;Aspects of Behavior in Pedophillic Sex Offenders Treated with Leuprolide Acetate;163
14.1;Summary;163
14.2;Introduction;164
14.3;Materials and Methods;165
14.4;Abel Assessment;165
14.5;Penile Plethysmography;166
14.6;Polygraph;167
14.7;Psychotherapy;168
14.8;Results;168
14.9;Discussion;169
14.10;References;172
15;The Brain, Androgens, and Pedophilia;175
15.1;Summary;175
15.2;Introduction;175
15.3;The Brain Is a Major Determinant of Sexual Behavior;176
15.4;Human Sexual Behavior Is Largely Dependent on Plasma Testosterone;183
15.5;Antihormonal Therapy in Pedophilia;183
15.6;References;185
16;Role of Alcohol and Sex Hormones on Human Aggressive Behavior;189
16.1;Summary;189
16.2;Introduction;190
16.3;Alcohol and Aggression;190
16.4;Testosterone and Aggression;190
16.5;Alcohol, Testosterone and Aggression;192
16.6;Role of Estradiol in Alcohol- and Testosterone-related Aggression;192
16.7;Conclusions;194
16.8;References;194
17;Social Neuroscience: Complexities to Be Unravelled;199
17.1;Summary;199
17.2;Introduction;199
17.3;The Social Brain;201
17.4;Social Experience Driving High Levels of Self Awareness?;203
17.5;Outlook;205
17.6;References;206
18;Subject Index;209
18.1;Previous titles in the book series Research and Perspectives in Endocrine Interactions;211