Prayson / Napekoski Frozen Section Library: Central Nervous System

1. Auflage 2010
ISBN: 978-1-4419-7579-9
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 6, 152 Seiten

Reihe: Frozen Section Library

Frozen section of Neuropathology-related cases is performed while the patient is undergoing surgery. Intraoperative consultation is used to help guide intraoperative management of the case and to ensure that adequate and appropriate tissue has been obtained for purposes of making an accurate final diagnosis. Frozen section diagnosis is often a highly demanding situation for the pathologist, who must render a diagnosis quickly and provide sound guidance and advice. In addition to the need for rapid recall of differential diagnoses, there are many pitfalls and artifacts that add to the risk of frozen section diagnosis that are not present with permanent sections of fully processed tissue that can be examined in a more leisurely fashion. Most standard pathology textbooks focus primarily on permanent section material and largely ignore the topic of frozen section. The purpose of this volume is to add to the Frozen Section Library series and provide a convenient, user friendly handbook to assist in the evaluation of central nervous system related frozen sections. It provides a useful reference, organized around differential diagnoses, primarily by location in the central nervous system. The text will be illustrated with color pictures and include tables as appropriate. This text provides a valuable tool for the practicing surgical pathologist both in community and in academic centers as well as pathology residents and fellows in training when confronted with Neuropathology frozen section.

Richard A. Prayson, MD, is at the Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH. Karl M. Napekoski, MD, is at the Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH.

Autoren/Hrsg.

Prayson, Richard A.

Napekoski, Karl M.

Inhaltsverzeichnis

1;Series Preface;6
2;Preface;8
3;Acknowledgments;10
4;Contents;12
5;Chapter 1: Introduction;14
5.1;UTILITY OF FROZEN SECTION IN THE EVALUATION OF NEUROPATHOLOGY CASES;14
5.2;FROZEN SECTION VERSUS SQUASH PREPARATIONS;17
6;Chapter 2: Where to Start;22
6.1;TISSUE HAS BEEN RECEIVED AND A FROZEN SECTION CONSULTATION REQUESTED. THEN WHAT?;22
6.2;WHERE AM I?;22
6.3;GLIOSIS OR SOMETHING MORE?;29
7;Chapter 3: Nonneoplastic Flags;32
7.1;FLAG 1: CHRONIC VASCULAR-BASED INFLAMMATION;32
7.2;FLAG 2: ACUTE INFLAMMATION;40
7.3;FLAG 3: GRANULOMATOUS INFLAMMATION;42
7.4;FLAG 4: MACROPHAGES;44
7.5;FLAG 5: THICKENED BLOOD VESSEL WALLS;49
7.6;FLAG 6: TOO MANY BLOOD VESSELS;50
7.7;FLAG 7: CYSTS;53
8;Chapter 4: Cerebral Parenchymal Lesions: I. Metastatic Neoplasms;57
9;Chapter 5: Cerebral Parenchymal Lesions: II. Primary Tumors;66
9.1;ASTROCYTOMAS;66
9.2;OLIGODENDROGLIOMAS;82
9.3;GLIONEURONAL TUMORS;85
9.4;OTHER TUMORS;88
10;Chapter 6: Dural-Based Tumors;90
10.1;THE Relatively GOOD;90
10.2;THE NOT SO GOOD;98
10.3;THE BAD;102
11;Chapter 7: Intraventricular Lesions;107
11.1;EPENDYMAL NEOPLASMS;107
11.2;CHOROID PLEXUS TUMORS;114
11.3;CENTRAL NEUROCYTOMA;116
11.4;OTHER TUMORS;118
12;Chapter 8: Cerebellar Lesions;121
12.1;IN KIDS;121
12.2;IN YOUNG ADULTS;126
12.3;IN OLDER ADULTS;130
13;Chapter 9: Pituitary Gland and Sellar Lesions;131
13.1;MOST TUMORS ARE ADENOMAS;131
13.2;BUT NOT ALL OF THEM;134
13.3;CRANIOPHARYNGIOMA;137
14;Chapter 10: Pineal Gland Lesions;140
14.1;GERMINOMAS AND GERM CELL TUMORS;140
14.2;EVERYTHING ELSE;141
15;Chapter 11: Spinal Cord Lesions;147
15.1;INTRAMEDULLARY;147
15.2;INTRADURAL, EXTRAMEDULLARY;148
15.3;EXTRADURAL;150
16;Suggested Readings;152
17;Index;154