Priestman Cancer Chemotherapy in Clinical Practice

1. Auflage 2007
ISBN: 978-1-84628-991-0
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 134 Seiten, Web PDF

Reihe: Medicine

This book is intended as a basic overview of the drug treatment of cancer for junior doctors and specialist nurses who come into contact with people having chemotherapy as part of their day-- day work. The aim is to provide a context to those treatments, explaining what the drugs are, how they work, some of their more likely side effects, how they are used in the treatment of the commoner cancers and what therapeutic results might be expected. The first use of the word chemotherapy is credited to Paul Ehrlich (1854–1915), who used it to describe the arsenical compounds he developed to treat syphilis. Nowadays when people talk about ‘chemotherapy’, as part of cancer treatment, they are usually referring to the use of cytotoxic drugs. Cytotoxics have dominated systemic cancer therapy for the last 50 years, and their use has resulted in enormous improvements in outcome. But they are only one component of the drug treatment of malignancy. Hormonal therapies are another major contributor toincreased cure rates and survival times, and the last decade has seen an explosion of entirely new types of drugs for cancer treatment. The latter are mainly drugs specifically targeted against cancer cells (whereas cytotoxics affect both normal and malignant cells). These newer compounds have sometimes been popularly termed ‘magic bullets’, which again takes us back to Ehrlich, as this was another phrase he used to describe his treatments.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Priestman, Terrence

Inhaltsverzeichnis

I. The relationship between tumour biology and chemotherapy: Introduction.- Genes and gene therapy.- Chemoprevention.- Receptors.- Signal transduction.- Cell division.- Tumour growth.- Metastasis.- II. Some Practical issues: Drug delivery.- Side effects and their management.- III. The role of systemic therapy in cancer management: Introduction.- Breast cancer.- Urological cancer.- Bowel Cancer.- Lung cancer.- Haematological cancer.- Upper gastrointestinal cancer.- Gynaecological cancer.- Head and neck cancer.- Brain tumours.

Über Autor(innen)

Dr Terrence J. Priestman is Clinical Director, Cancer Services, New Cross Hospital Wolverhampton, UK; Honorary Senior Clinical Lecturer, University of Birmingham, UK; and Series Editor, Cancer BACUP publications. In addition to having published numerous articles and contributed 16 chapters, he also wrote 4 books on cancer chemotherapy, gastrointestinal cancer, coping with chemotherapy, and coping with breast cancer. He was founder editor of Clinical Oncology, deputy editor of Clinical Radiology, and editorial board member of British Journal of Cancer and Cancer Immunology & Immunotherapy. He has also been writing for the charity "Cancerbackup", which provides information to cancer patients and their carers.