Rainsford Ibuprofen: Pharmacology, Therapeutics and Side Effects

1. Auflage 2013
ISBN: 978-3-0348-0496-7
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 243 Seiten, eBook

Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions. Over the past 40 years, ibuprofen has been proven to be as safe or even safer and also as effective as the established non-steroidal anti-inflammatory drugs (NSAIDs) and the coxibs. This well-written book reviews the pharmacology, clinical uses and the various adverse effects of Ibuprofen, the disposition and unique modes of action in relation to clinical effects of the drug as well as various formulations. The use of combinations with other drugs (e.g. paracetamol, codeine, caffeine) are critically assessed and the impact of natural products and Chinese Medicines on the safety of ibuprofen.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Rainsford, K. D.

Inhaltsverzeichnis

Introduction.- Biodisposition in relation to actions.- Mechanisms of inflammation and sites of action of NSAIDs.- Clinical efficacy.- Drug derivatives and formulations.- General safety profile.- Gastro-intestinal toxicity.- Cardiovascular safety.- Renal toxicity.- Hepatic toxicity.- Other adverse reactions.- Global assessment of adverse reactions & human toxicology.- Overall assessment.