Ramsay Thyroid Disease and Muscle Dysfunction

1. Auflage 2013
ISBN: 978-1-4831-9300-7
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 190 Seiten, Web PDF

Thyroid Disease and Muscle Dysfunction covers the pioneering work of the author in the study of muscle dysfunction in patients with thyrotoxicosis. His contributions on this subject represent real advances in the understanding of metabolic muscle disease. This book is written to clarify the association between abnormalities of skeletal muscle and derangement of thyroid function. This book is organized into five chapters that describe the muscular abnormalities in people with hypothyroidism, explain the concepts of thyrotoxic periodic paralysis and thyrotoxic myopathy, discuss the association between thyroid disease and myasthenia gravis, and describe the changes in thyroid functions associated with miscellaneous muscle disorders. This book will be of interest to persons dealing with studies on the relation between thyroid disease and muscle dysfunction.

Autoren/Hrsg.

Ramsay, Ian

Inhaltsverzeichnis

1;Front Cover;1
2;Thyroid Disease and Muscle Dysfunction;4
3;Copyright Page;5
4;Table of Contents;12
5;Dedication;6
6;FOREWORD;7
7;PREFACE;8
8;ACKNOWLEDGEMENTS;10
9;CHAPTER 1. THYROTOXIC MYOPATHY;14
9.1;Analysis of the literature on 73 patients wiht "chronic thyrotoxic myopathy";15
9.2;Unselected thyrotoxic piatients;16
9.3;Electromyography;22
9.4;Achilles tendon reflex time;29
9.5;Biochemistry;29
9.6;Muscle potassium and sodium;30
9.7;Creatine and creatinine metabolism;31
9.8;Calcium and magnesium metabolism;32
9.9;Pyridoxine;33
9.10;Muscle enzymes;33
9.11;Steroid hormone metabolism in thyrotoxicosis;34
9.12;Muscle pathology;34
9.13;Electron microscopy ;38
9.14;Experimental pathology;39
9.15;Relationship between structure and function;42
9.16;Aetiology of myopathy;44
9.17;Why proximal myopathy?;45
9.18;The role of catecholamines in thyrotoxic myopathy;48
9.19;Differential diagnosis of thyrotoxic myopathy;49
9.20;REFERENCES;53
10;CHAPTER 2. THYROID DISEASE AND MYASTHENIA GRAVIS;65
10.1;Prevalence;65
10.2;Investigations;77
10.3;D-Tubocurarine;78
10.4;Decamethonium;78
10.5;Electromyography;79
10.6;Pathology of muscle;81
10.7;Types of fibre atrophy;82
10.8;Motor nerve endings;83
10.9;Pathology of the thymus;84
10.10;In myasthenia gravis;84
10.11;In Thyrotoxicosis;84
10.12;Endocrine function of the thymus;86
10.13;Thymoma and thyrotoxicosis;90
10.14;Thymectomy;90
10.15;Myasthenia gravis, hypothyroidism and thyroidtis;90
10.16;The thymus in myasthenic patients with Hashimoto's thyroiditis or myxoedema;92
10.17;Effect of hypothyroidism on myasthenia;92
10.18;Association of myasthenia gravis with other thyroid diease;94
10.19;Hereditary factors;95
10.20;The site of action of thyroid hormone in myasthenia gravis;97
10.21;Conclusions;100
10.22;REFERENCES;101
11;CHAPTER 3. THYROTOXIC PERIODIC PARALYSIS;109
11.1;Prevalence;109
11.2;Clinical features;112
11.3;Induction of attacks;113
11.4;The effect of thyroid hormone;114
11.5;Potassium and sodium;118
11.6;Magnesium and calcium;122
11.7;(Satoyoshi et al.,1963a);123
11.8;Carbohydrate metabolism;123
11.9;Light microscopy;124
11.10;Electron microscopy;129
11.11;Aetiology;132
11.12;REFERENCES;135
12;CHAPTER 4. MUSCULAR ABNORMALITIES OF HYPOTHYROIDISM;139
12.1;Kocher–Debré-Semelaigne syndrome;139
12.2;Hoffman's syndrome;141
12.3;Muscle atrophy;142
12.4;Other muscle diseases;142
12.5;Hypothyroid myopathy;142
12.6;Hypothyroid neuropathy;147
12.7;Reflex duration;148
12.8;Electromyography;151
12.9;Biochemistry;156
12.10;Creatine and creatinine;156
12.11;Creatine phosphokinase;156
12.12;Other muscle enzymes;159
12.13;Magnesium;160
12.14;Sodium and potassium;160
12.15;Pathology;160
12.16;Aetiology of hypothyroid myopathy;175
12.17;REFERENCES;177
13;CHAPTER 5. THYROID FUNCTION IN MISCELLANEOUS MUSCLE DISORDERS;185
13.1;Myotonia congenita;185
13.2;Myotonic dystrophy;185
13.3;Muscular dystrophy;186
14;INDEX;188