E-Book, Englisch, 216 Seiten
Reihe: Medical Intelligence Unit
Razzaque Fibrogenesis
1. Auflage 2007
ISBN: 978-0-387-26476-9
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark
Cellular and Molecular Basis
E-Book, Englisch, 216 Seiten
Reihe: Medical Intelligence Unit
ISBN: 978-0-387-26476-9
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark
Fibrogenesis: Cellular and Molecular Basis is the first volume to provide a synopsis of the rapid progress that has been documented in fibrogenesis over last couple of years, which significantly enhanced our understanding of the pathomechanisms of fibrotic diseases. Knowledge on molecular and celluar basis of fibrotic diseases has provided opportunities to develop selective and effective gene-based therapeutic options. The chapters in this book have been selected to provide comprehensive information on fibrogenesis, which is not limited to any specific organ. Individual chapters present mechanisms of fibrotic diseases involving lung, liver, kidney, heart, blood vessels, and more. The relevance and significance of inflammatory cytokines, chemokines, transcriptional factors, fibrogenic molecules, signaling cascade, and matrix remodeling in fibrogenesis are explained in depth, providing the reader with current and updated information.
Autoren/Hrsg.
Weitere Infos & Material
1;CONTENTS;5
2;EDITOR;9
3;CONTRIBUTORS;9
4;PREFACE;13
5;ABBREVIATIONS;14
6;Tissue Scarring: Lessons from Wound Healing;15
7;Pathological Significance of Renal Expression of Proinflammatory Molecules;23
8;Oxidative Stress, Lipoproteins and Angiotensin II: The Unholy Triad in the Pathogenesis of Renal Fibrosis;41
9;Involvement of NF-KB in Renal Inflammation and Sclerosis;52
10;Low- Density Lipoprotein and Glomerulosclerosis;59
11;Molecular Developments in the Treatment of Renal Fibrosis;75
12;Myocardial Infarction and Cardiac Fibrogenesis;91
13;Cardiac Fibrosis and Aging;111
14;Matrix Remodeling and Atherosclerosis Effect of Age;118
15;Molecular and Cellular Aspects of Liver Fibrosis;132
16;Recent Therapeutic Developments in Hepatic Fibrosis;136
17;Reversibility of Liver Fibrosis: Role of Matrix Metalloproteinases;157
18;Can Manipulation of Apoptotic Cell Death Benefit Tissue Scarring?;174
19;Pulmonaiy Fibrogenesis: The Role of Apoptosis and Its Clinical Potentials;192
20;Silica-Induced Inflammatoiy Mediators and Pulmonary Fibrosis;213
21;INDEX;225
