Regazzi Molecular Mechanisms of Exocytosis

1. Auflage 2008
ISBN: 978-0-387-39961-4
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 178 Seiten

Reihe: Molecular Biology Intelligence Unit

This book examines the role of key components in the exocytotic process, not only in neuronal and endocrine cells but in a variety of other relevant cell systems. So far, because of the large number of components involved, understanding of the molecular basis of exocytosis has remained the privilege of a relatively small group of specialists. The book collects up-to-date reviews from the forefront of this fascinating and rapidly evolving field.

Autoren/Hrsg.

Regazzi, Romano

Inhaltsverzeichnis

1;CONTENTS;4
2;PREFACE;7
3;EDITOR;8
4;CONTRIBUTORS;8
5;Exocytosis: Lessons from SNARE Mutants and Friends;10
6;Regulation of SNARE Complex Assembly by Second Messengers: Roles of Phospholipases, Munc 13 and Munc 18;19
7;Rab GTPases and Their Role in the Control of Exocytosis;37
8;The Role of Synaptotagmin and Synaptotagmin-Like Protein (Slp) in Regulated Exocytosis;51
9;The Synapsins and the Control of Neuroexocytosis;71
10;Phospholipase D: A Multi-Regulated Lipid-Modifying Enzyme Involved in the Late Stages of Exocytosis;84
11;Lipid Rafts as Regulators of SNARE Activity and Exocytosis;93
12;Mast Cells as a Model of Nonneuroendocrine Exocytosis;109
13;Acrosomal Exocytosis;126
14;Nonsecretory, Regulated Exocytosis: A Multifarious Mechanism Employed by Cells to Carry Out a Variety of Functions;157
15;Adaptation of the Secretory Machinery to Pathophysiological Gonditions;170
16;Index;183