Sadana Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals

1. Auflage 2006
ISBN: 978-0-08-046369-8
Verlag: Elsevier Science & Techn.
Format: EPUB
Kopierschutz: 6 - ePub Watermark

E-Book, Englisch, 385 Seiten

The application of biosensors is expanding in different areas. These are portable and convenient devices that permit the rapid, accurate, and reliable detection of analytes of interest present either in the atmosphere or in aqueous or in liquid phases. The detection of glucose levels in blood for the effective management of diabetes is one. Though different biosensors have been designed for an increasing number of applications, the kinetics of binding (and dissociation) of analytes by the receptors on the biosensor surfaces has not been given enough attention in the open literature. This is a very important area of investigation since it significantly impacts biosensor performance parameters such as stability, sensitivity, selectivity, response time, regenerability, etc. Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals addresses this critical need besides helping to correct or demonstrate the need to modify the present software available with commercial biosensors that determines the kinetics of analyte-receptor reactions on biosensor surfaces.
* first book to provide detailed kinetic analysis of the binding and dissociation reactions that are occuring on the biosensor surface
* addresses the area of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces
* provides physical insights into reactions occuring on biosensor surfaces

Autoren/Hrsg.

Sadana, Ajit

Inhaltsverzeichnis

1;Cover;1
2;Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals;4
3;Copyright page;5
4;Foreword;8
5;Preface;10
6;Contents;12
7;Chapter 1. Introduction;16
7.1;1.1 Definition of Biosensors;16
7.2;1.2 Current and Future Applications;19
7.3;1.3 Biosensor Economics;24
7.4;1.4 Overview;25
7.5;References;27
8;Chapter 2. Modeling and Theory;32
8.1;2.1 Introduction;32
8.2;2.2 Theory;35
8.3;References;43
9;Chapter 3. Fractal Analysis of Toxin and Pathogen Detection on Biosensor Surfaces;46
9.1;3.1 Introduction;46
9.2;3.2 Theory;47
9.3;3.3 Results;49
9.4;3.4 Conclusions;67
9.5;References;69
10;Chapter 4. Fractal Binding and Dissociation Kinetics of Heart-Related Compounds on Biosensor Surfaces;72
10.1;4.1 Introduction;72
10.2;4.2 Theory;73
10.3;4.3 Results;75
10.4;4.4 Conclusions;104
10.5;References;105
11;Chapter 5. Fractal Analysis of Binding and Dissociation Kinetics and Interactions of Cancer Markers on Biosensor Surfaces;108
11.1;5.1 Introduction;108
11.2;5.2 Theory;109
11.3;5.3 Results;111
11.4;5.4 Conclusions;123
11.5;References;124
12;Chapter 6. Fractal Analysis of Binding and Dissociation of Autoimmune Disease Markers on Biosensor Surfaces;126
12.1;6.1 Introduction;126
12.2;6.2 Theory;127
12.3;6.3 Results;129
12.4;6.4 Conclusions;148
12.5;References;150
13;Chapter 7. Fractal Binding and Dissociation Kinetics of Prion Proteins on Biosensor Surfaces;152
13.1;7.1 Introduction;152
13.2;7.2 Theory;153
13.3;7.3 Results;155
13.4;7.4 Conclusions;173
13.5;References;174
14;Chapter 8. Detection of Environmental Contaminants by Biosensors;176
14.1;8.1 Introduction;176
14.2;8.2 Theory;179
14.3;8.3 Results;181
14.4;8.4 Conclusions;208
14.5;References;209
15;Chapter 9. Fractal Analysis of Proteins Involved in Drug Design on Biosensor Surfaces;214
15.1;9.1 Introduction;214
15.2;9.2 Theory;215
15.3;9.3 Results;217
15.4;9.4 Conclusions;230
15.5;References;232
16;Chapter 10. Sol–Gel Biosensor Applications;234
16.1;10.1 Introduction;234
16.2;10.2 Theory;235
16.3;10.3 Results;237
16.4;10.4 Conclusions;253
16.5;References;255
17;Chapter 11. Novel Biosensing Methods;258
17.1;11.1 Introduction;258
17.2;11.2 Theory;259
17.3;11.3 Results;261
17.4;11.4 Conclusions;285
17.5;References;286
18;Chapter 12. Fractal Analysis of the Binding and Dissociation of Different Compounds on Biosensor Surfaces;288
18.1;12.1 Introduction;288
18.2;12.2 Theory;289
18.3;12.3 Results;291
18.4;12.4 Conclusions;329
18.5;References;331
19;Chapter 13. Market Size and Economics for Biosensors;334
19.1;13.1 Introduction;334
19.2;13.2 Biosensor Trends and Collaborations between Companies and State and Governmental Agencies;339
19.3;13.3 Commercial Development of Biosensors;341
19.4;13.4 Biosensor Technologies and Techniques;342
19.5;13.5 Examples of Small and Medium Biosensor Companies that are either Successful or are on the way to be Successful;346
19.6;13.6 Factors that could help Increase Biosensor Markets;350
19.7;13.7 Examples of Size of Grants and Financing from Different Sources;351
19.8;13.8 Conclusions;353
19.9;References;354
20;Index;358