Santini / Ward | The Metabolism of Arsenite | E-Book | www.sack.de
E-Book

E-Book, Englisch, 218 Seiten

Reihe: Arsenic in the environment

Santini / Ward The Metabolism of Arsenite


1. Auflage 2012
ISBN: 978-1-136-31955-6
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 218 Seiten

Reihe: Arsenic in the environment

ISBN: 978-1-136-31955-6
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)



Up to 200 million people in 70 countries are at risk from drinking water contaminated with arsenic, which is a major cause of chronic debilitating illnesses and fatal cancers. Until recently little was known about the mobility of arsenic, and how redox transformations determined its movement into or out of water supplies. Although human activities contribute to the release of arsenic from minerals, it is now clear that bacteria are responsible for most of the redox transformation of arsenic in the environment. Bacterial oxidation of arsenite (to the less mobile arsenate) has been known since 1918, but it was not until 2000 that a bacterium was shown to gain energy from this process. Since then a wide range of arsenite-oxidizing bacteria have been isolated, including aerobes and anaerobes; heterotrophs and autotrophs; thermophiles, mesophiles and psychrophiles. This book reviews recent advances in the study of such bacteria. After a section on background—geology and health issues—the main body of the book concerns the cellular machinery of arsenite oxidation. It concludes by examining possible applications. Topics treated are:

- The geology and cycling of arsenic

- Arsenic and disease

- Arsenite oxidation: physiology, enzymes, genes, and gene regulation.

- Community genomics and functioning, and the evolution of arsenite oxidation

- Microbial arsenite oxidation in bioremediation

- Biosensors for arsenic in drinking water and industrial effluents

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Weitere Infos & Material


Arsenic in the environment

D. Kossoff & K.A. Hudson-Edward
Introduction
Chemistry and mineralogy of arsenic

Distribution of arsenic in the environment

Processes of arsenic cycling in the environment

Giant Mine,Yellowknife, Canada: Arsenite waste as the legacy of gold mining and processing

M. Bromstad & H.E. Jamieson
Introduction

Background

Arsenic and arsenite in mine wastes and surrounding area

Transformation and remobilization of arsenic species

Site remediation

Summary

Genotoxic and carcinogenic risk of arsenic exposure. Influence of interindividual genetic variability

R. Marcos & A. Hernández
Introduction

Carcinogenic risk

Genotoxic risk

Genetic polymorphisms affecting carcinogenic risk

Genetic polymorphisms affecting genotoxic risk

Conclusions

Overview of microbial arsenic metabolism and resistance

J.F. Stolz
Introduction

Arsenic resistance

Arsenic in energy generation
Prokaryotic aerobic oxidation of arsenite

T.H. Osborne & J.M. Santini
Introduction

Aerobic arsenite-oxidizing bacteria

Arsenite metabolism

Aerobic arsenite-oxidizing communities

Summary and future directions

Anaerobic oxidation of arsenite by autotrophic bacteria: The view from Mono Lake, California

R.S. Oremland, J.F. Stolz & C.W. Saltikov
Introduction

Nitrate-respiring arsenite-oxidizers

An annotated arsenate reductase that runs in reverse

Anoxygenic photosynthesis fueled by arsenite

Arsenite oxidase

M.D. Heath, B. Schoepp-Cothenet, T.H. Osborne & J.M. Santini
Introduction

Characteristics of the arsenite oxidase

Microbial arsenic response and metabolism in the genomics era

P.N. Bertin, L. Geist, D. Halter, S. Koechler, M. Marchal & F. Arsène-Ploetze
Introduction

Descriptive and comparative genomics

High-throughput genomics reveal the functioning of microorganisms

Conclusions

Arsenite oxidation – regulation of gene expression
M.Wojnowska & S. Djordjevic

Introduction

Multiple modes of arsenite oxidase regulation

AioSR and their involvement in Aio regulation

Quorum sensing

Heat-shock protein DNAJ

Conclusions

Evolution of arsenite oxidation

R. van Lis,W. Nitschke, S. Duval & B. Schoepp-Cothenet
Introduction

Molecular description of arsenic bioenergetic enzymes

Function of the enzymes

Phylogenetic analysis of Aio and Arr

Taking bioenergetics into account

Evolutionary scenario of arsenite oxidation

Remediation using arsenite-oxidizing bacteria
F. Delavat, M.-C. Lett & D. Lièvremont
Introduction
Arsenite oxidation-based remediation bioprocesses

Conclusion

Development of biosensors for the detection of arsenic in drinking water
C. French, K. de Mora, N. Joshi, J. Haseloff & J. Ajioka

Introduction

Biosensors for detection of environmental toxins

Biosensors for arsenic

Conclusions
Subject index



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