Buch, Englisch, 396 Seiten, Format (B × H): 172 mm x 245 mm, Gewicht: 908 g
Buch, Englisch, 396 Seiten, Format (B × H): 172 mm x 245 mm, Gewicht: 908 g
ISBN: 978-0-470-01780-7
Verlag: Wiley-Blackwell
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Chemie Chemie Allgemein Toxikologie, Gefahrstoffe, Sicherheit in der Chemie
- Naturwissenschaften Chemie Chemie Allgemein Chemische Labormethoden, Stöchiometrie
- Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
- Naturwissenschaften Chemie Chemie Allgemein Chemometrik, Chemoinformatik
Weitere Infos & Material
Preface.
1. Introduction.
1.1 Role of chemistry in modern life.
1.2 Physical properties of drug molecules.
2. Atomic structure and bonding.
2.1 Atoms, elements and compounds.
2.2 Atomic structure: orbitals and electronic configurations.
2.3 Chemical bonding theories: formation of chemical bonds.
2.4 Electronegativity and chemical bonding.
2.5 Bond polarity and intermolecular forces.
2.6 Significance of chemical bonding in drug-receptor interactions.
3. Stereochemistry.
3.1 Stereochemistry: definition.3.2 Isomerism.
3.3 Significance of stereoisomerism in determining drug action and toxicity.
3.4 Synthesis of chiral molecules.
3.5 Separation of stereoisomers: resolution of racemic mixtures.
3.6 Compounds with stereocentres other than carbon.
3.7 Chiral compounds that do not have a tetrahedral atom with four different groups.
4. Organic functional groups.
4.1 Organic functional groups: definition and structural features.
4.2 Hydrocarbons.
4.3 Alkanes, cycloalkanes and their derivatives.
4.4 Alkenes and their derivatives.
4.5 Alkynes and their derivatives.
4.6 Aromatic compounds and their derivatives.
4.7 Heterocyclic compounds and their derivatives.
4.8 Nucleic acids.
4.9 Amino acids and peptides.
4.10 Importance of functional groups in determining drug actions and toxicity.
4.11 Importance of functional groups in determining stability of drugs.
5. Organic reactions.
5.1 Types of organic reaction.
5.2 Radical reactions: free radical chain reactions.
5.3 Addition reactions.
5.4 Elimination reactions: 1,2-elimination or ß-elimination.
5.5 Substitution reactions.
5.6 Hydrolysis.
5.7 Oxidation?reduction reactions.
5.8 Pericyclic reactions.
6. Natural product chemistry.
6.1 Introduction to natural products drug discovery process.
6.2 Alkaloids.
6.3 Carbohydrates.
6.4 Glycosides.
6.5 Terpenoids.
6.6 Steroids.
6.7 Phenolics.
