In Silico Life Sciences: Medicine
E-Book, Englisch, 309 Seiten, eBook
ISBN: 978-3-030-18375-2
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: Wasserzeichen (»Systemvoraussetzungen)
Our second title of this volume set In Silico Life Sciences: Medicine provides hands-on experience in analyzing high throughput molecular data for the diagnosis, prognosis, and treatment of monogenic or polygenic human diseases. The key concepts in this volume include risk factor assessment, genetic tests and result interpretation, personalized medicine, and drug discovery. This volume is expected to train readers in both single and multi-dimensional biological analysis using open data sets, and provides a unique learning experience through clinical scenarios and case studies.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
1. Bioinformatics strategies for molecular diagnostics o Candidate gene selection and analysis of Rare diseaseso Candidate gene selection and analysis of Complex diseases2. Bioinformatics tools for Molecular Diagnosticso Single Gene Disorders – Case studieso Polygenic Disorders – Case studieso Genetic Tests – Tools, Results, Interpretation3. Bioinformatics approaches for Genetic Risk Marker Studieso Population Geneticso Gene Polymorphismso Gene Expression Assayso Genetic Statistics4. Bioinformatics for Disease Prognosticso Pharmacogeneticso Efficacyo Toxicityo Adverse reactions o Biomarker Selection and Monitoringo Precision Medicine5. Bioinformatics tools in Gene Therapyo Enzyme Replacement- Bioinformatics role is limitedo Gene Replacement (Knock-in)o Gene Silencing(RNAi)o Gene Editing (CRISPR)6. Bioinform
atics tools in Disease Therapeutics – Data analysis tools and application
o Drug Discovery o Protein-Drug Interactionso Drug-Body metabolism studieso Microbiome