Shimonishi / University / (Ed.) Peptide Science - Present and Future

Proceedings of the 1st International Peptide Symposium
1. Auflage 2007
ISBN: 978-0-306-46864-3
Verlag: Springer Netherlands
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 896 Seiten

Bioorganic Chemistry - Short description currently not available.

Autoren/Hrsg.

Shimonishi, Yasutsugu

University, Osaka

(Ed.), Japan

Inhaltsverzeichnis

1;Contents;5
2;Preface;35
3;First International Peptide Symposium;37
4;Acknowledgements;39
5;Abbreviations;41
6;From big molecules to smaller ones;47
7;Directions for solving the remaining problems in the synthesis of large peptides;52
8;Theoretical analysis of ßaßaß-type packing motifs formed by alternate intramolecular arrangements of three a-helices and three ß-strands;141
9;Characterization of sulfhydryl compounds attached to the cysteinyl residue of proteins or peptides by on-line post-column derivatization;198
10;Regioselective hydrolytic cleavage of N-terminal myristoyl-peptide;200
11;Determination of the binding-site structure of the atrial natriuretic peptide receptor by stepwise-affinity alkylation;209
12;A novel type of rat brain d opioid receptors differenciated by cyclopropylphenylalanine-containing enkephalin analog;253
13;Conformational analysis of peptide fragments corresponding to domains of potassium ion- channel proteins;301
14;Formation of native disulphide bonds in endothelin-1: evidence for the involvement of a highly specific salt-bridge between the pro-sequence of endothelin-1 and mature sequence;312
15;Sequence, conformation, and function of peptides, retro peptides and sense and antisense gene products;359
16;Topological isomers of human uroguanylin: structure determination by nuclear magnetic resonance;370
17;Circular dichroism and fluorescence study of the interaction of synthetic J protein from bacteriophage fK with DNA;419
18;Unusual collagen assembly induced by acidic biopolymers in vitro;422
19;Nociceptin, a novel neuropeptide with multiple functions;434
20;An anti-HIV peptide T22 is confirmed to be a selective CXCR4/ fusin inhibitor by comparative inhibition study of a chemokine SDF- 1, synthesized by regioselective disulfide bond formation;444
21;Effect of carnosine and its natural derivatives on apoptosis of neurons induced by excitotoxic compounds;459
22;Purification of peptide fractions with anticomplementary activity from red ginseng (Panax ginseng, C.A. Meyer);467
23;Chemical and biological characterization of neuropeptides in the sinus glands of the kuruma prawn, Penaeus japonicus;499
24;Macrotorials: synthesis and characterization of model compounds related to PTH (1 – 34);518
25;Combined solid-phase and solution approach to protein synthesis;536
26;Enzymatic peptide synthesis using activated esters as acyl donors in organic media;560
27;Studies of racemization in peptide synthesis for a phosphoryloxy-benzotriazin-one coupling reagent (DEPBT);576
28;Diastereoselective synthesis of glycosyl- a-aminoacids and glycopeptide derivatives;641
29;Influence of glycation on cis/trans isomerization and tautomerization in novel morphiceptin-related Amadori compounds;646
30;Design of novel, nonpeptide oxytocin receptor antagonists;664
31;The substrate specificity of microbial carboxyl proteinases;703
32;Allophenylnorstatine containing HIV-1 protease inhibitors: design, synthesis and structure – activity relationships for selected P2 and P2' ligands;706
33;Cell specific gene transfer using galactose-modified peptide;755
34;Synthesis and biological activities of hPTH(1–34) analogues: modification of the middle part and C-terminal alkylamides;757
35;Hybridization properties of nucleic acid analogs bearing peptide backbone;791
36;Physiological role of the delta sleep-inducing peptide (DSIP);803
37;Effect of nitroprusside on amyloid ß-peptide induced inhibition of MTT reduction in pheochromocytoma PC12h and C1300 neuroblastoma cells;823
38;Molecular design of T cell-costimulatory peptides for vaccine development;847
39;The identification of dominant epitopes of h-FKBP-12 recognized by monoclonal antibodies, 3F4 and 2C1, against h-FK-506 binding protein 12(h-FKBP-12);849
40;Conformational and binding studies of the peptide isolated from phage display library by anti- mouse CTLA-4 monoclonal antibody;856
41;Formation of DNA-anti-DNA antibody immune complex on collagen matrix;859
42;Natural IgM antibodies against human endogenous retroviruses HERV-H demonstrated by means of synthetic peptides;862
43;Evaluation of region-specific antibodies for rat and human Chromogranin A with use of synthetic peptide;864
44;Design of synthetic antigen containing nonimmunogenic T cell epitope core and simple nonnative flanking regions;866
45;Immune response to newly exposed regions of Band 3 protein of the red blood cell membrane during malaria infections;869
46;Peptide-induced antibodies as a tool to link genomes and proteomes;871
47;Porphyrin-peptide conjugates with stabilized helices and sheets;874
48;Molecular recognition of cyclic HIV protease inhibitors: highly orally-bioavailable DMP851;877
49;Index;879