Smit Sibinga / Das / Briët Hereditary Diseases and Blood Transfusion

Proceedings of the Nineteenth International Symposium on Blood Transfusion, Groningen 1994, organized by the Red Cross Blood Bank Groningen-Drenthe
1995
ISBN: 978-1-4615-2017-7
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 30, 259 Seiten, eBook

Reihe: Developments in Hematology and Immunology

Proceedings of the Nineteenth Annual International Symposium on Blood Transfusion, Groningen 1994, organized by the Red Cross Blood Bank, Groningen--Drenthe

Zielgruppe

Research

Autoren/Hrsg.

Smit Sibinga, C.Th.

Das, P.C.

Briët, E.

Inhaltsverzeichnis

I. Blood coagulation: molecular biology of haemophilia, various types of von Willebrand disease and thrombophilia. II. Haemoglobin and red cells: globin gene regulation, molecular pathology of thalassaemia syndromes, options for bone marrow transplantation and gene therapy for haemoglobinopathies, molecular biology and genetic abnormalities in blood group serology. III. White cells and malignancies: role of the Blood Bank in human gene therapy trials and translocations in cancer, mechanism of oncogenic conversion and implications for therapy, role of topoisomerase IIalpha and beta isozymes in determining intrinsic and acquired drug resistance. IV. Gene technology, ethics and the future: ethics of genetic manipulation, impact of cell culture technology on transfusion medicine, strategies for making gene therapy work, the role of the Blood Bank in gene therapy.