Spengler / Binder Epigenetics and Neuroendocrinology

Clinical Focus on Psychiatry, Volume 1
1. Auflage 2016
ISBN: 978-3-319-24493-8
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 264 Seiten

Reihe: Biomedical and Life Sciences (R0)

The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the development of the neuroendocrine axes as well as in the mediation of gene-environment interactions in stress-related psychiatry disorders.

Zielgruppe

Research

Autoren/Hrsg.

Spengler, Dietmar

Binder, Elisabeth

Inhaltsverzeichnis

Foreword by Dietmar Spengler & Elisabeth Binder.- Part I, Epigenetics And The Stress System.- I.1 From vulnerability to neurotoxicity: A developmental approach to the effects of stress on brain and behavior .- I.2 Dynamic regulation of chromatin modification and transcription by GR and the steroid receptors .- I.3 NR receptor coactivators.- I.4 Glucocorticoid-dependent epigenetic regulation of Fkbp5.- I.5Epigenetic programming of the HPA axis by early-life adversity.- I.6 Epigenetic programming of hypothalamic Pomc regulates feeding and obesity.- I.7 Effects of maternal care in monkeys.- I.8 Stress, transposons and the brain epigenome.- Part II; Epigenetics And Sexual Differentiation.- II.1 Neuroepigenetics of sexual differentiation of brain and behavior.- II.2 Differential regulation of androgen receptor and DNA methylation in songbirds.- II.3 chapter title "GnRH gene/Kiss gene, sexual dimorphism, puberty.