Srivastava / Kumar / Singh Xenobiotics in Chemical Carcinogenesis

Translational Aspects in Toxicology
1. Auflage 2022
ISBN: 978-0-323-90681-4
Verlag: Elsevier Science & Techn.
Format: EPUB
Kopierschutz: 6 - ePub Watermark

E-Book, Englisch, 328 Seiten

Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology covers the translational toxicology of xenobiotics substances in carcinogenesis by explaining the toxicokinetic and toxicodynamic, toxicogenomic, biotransformation, and resistance mechanisms in the human body. The book begins with a historical review and link to future prospects for chemical carcinogenesis. It discusses major environmental xenobiotics and their risks in inducing cancer, along with content on toxic xenobiotics and their routes of exposure in humans, the role of xenobiotic metabolism in carcinogenesis, and the toxicokinetic and toxicodynamic of xenobiotics in cancer development. Lastly, the book explores current achievements such as using toxicogenomics for predicting the carcinogenicity of xenobiotic substances and the challenges posed by carcinogenic xenobiotic substances when examining preventive methods, diagnosis, and the development of anticancer drugs for specific toxicants. - Covers the exposure and transmission of various toxic xenobiotics substances, including nanomaterials, to humans and their interaction with specific tissues in precipitating the development of cancers - Unravels the toxicokinetic and toxicodynamic processes of toxic xenobiotics in bioaccumulation - Examines the genetic aberrations in cancer genomes by genetic-environmental interactions in carcinogenesis - Explains the biotransformation mechanisms of toxic xenobiotics by gut microbes in humans

Dr. Mamta Bisht is presently working as an Assistant Professor in Department of Chemistry, School of Applied and Life Sciences, Uttaranchal University (NAAC A+), Dehradun, Uttarakhand India. She is actively involved in the extraction, isolation, characterization of 'Natural Products” obtained from the medicinal and aromatic plants with bioactivity since last 8 years. Besides this her analytical skill is in GC, GC-MS, HPLC, Prep- HPLC and HPTLC. Further, she is equally involved in the promotion of endangered and economically important species from the Youngest Himalayan region. She has been published more than fifteen papers in peer-reviewed international journal and seven book chapter. Further, she has been participated more than ten conferences including national and international. She is life time member of Indian Science Congress Association. Under her guidance many P.G. and U.G. student successfully completed her Project Thesis and some students are working with her. She is also guided the Ph. D students in the University.

Autoren/Hrsg.

Srivastava, Akhileshwar Kumar

Kumar, Dhruv

Singh, Divya

Singh, Rajesh Kumar