Sun Macro-Glycoligands

Methods and Protocols
1. Auflage 2016
ISBN: 978-1-4939-3130-9
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 1367, 226 Seiten, eBook

Reihe: Methods in Molecular Biology

This volume details methods and protocols for the synthesis and characterization of glycopolymers and their biomedical applications. Chapters are divided into three parts covering synthesis and characterization of glycopolymers; glycopolymer-nanoparticle conjugates; and surface immobilized glycopolymers.  Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Macro-Glycoligands: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Sun, Xue-Long

Inhaltsverzeichnis

Part I: Synthesis and Characterization of Glycopolymers 1. Synthesis of Chain-end Functionalized Glycopolymers via Cyanoxyl Mediated Free Radical Polymerization (CMFRP)Valentinas Gruzdys, Jinshan Tang, Elliot Chaikof, Xue-Long Sun 2. Protecting-group-free Synthesis of Well-defined Glycopolymers Featuring Negatively Charged OligosaccharidesLuca Albertin 3. Glycopolymers Prepared by Ring-opening Metathesis Polymerization Followed by Glycoconjugation Using a Triazole Forming ‘Click’ ReactionRonald Okoth and Amit Basu 4. Protecting-group-free Synthesis of Glycopolymers and Their Binding Assay with Lectin and Influenza VirusTomonari Tanaka, Tadanobu Takahashi, and Takashi Suzuki 5. Carbohydrate-based Initiators for the Cationic Ring-opening Polymerization of 2-Ethyl-2-oxazolineChristine Weber,Michael Gottschaldt, Richard Hoogenboom, Ulrich S. Schubert 6. Heterofunctional Glycopolypeptides by Combination of Thiol-ene Chemistry and NCA PolymerizationKai-Steffen Krannig and Helmut Schlaad 7. Preparation of Proteoglycan Mimetic Graft CopolymersMatt J. Kipper and Laura W. Place  Part II: Glycopolymer Nanoparticle Conjugates 8. Galactosylated Polymer Nano-objects by Polymerization-Induced Self-Assembly, Potential Drug NanocarriersMona Semsarilar, Irene Canton, and Vincent Ladmiral 9. Synthetic Approach to Biotinylated Glyco-Functionalized Quantum Dots: A New Fluorescent Probes for Biomedical ApplicationsChristian K. Adokoh, James Darkwa, and Ravin Narain 10. Surface Modification of Polydivinylbenzene Microspheres with a Fluorinated Glycopolymer using Thiol-Halogen Click ChemistryWentao Song and Anthony M. Granville 11. Glycopolymer-grafted Polymer Particles for Lectin RecognitionMichinari Kohri, Tatsuo Taniguchi, and Keiki Kishikawa 12. Synthesis of Non-spherical Glycopolymer-decorated Nanoparticles: Combing Thiol-ene with Catecholic ChemistryXiao Li, Weidong Zhang,and  Gaojian Chen 13. Synthetic Approach To Glycopolymer Base Nanoparticle Gold(I) Conjugate: A New Generation Of Therapeutic AgentsChristian K. Adokoh, James Darkwa, and Ravin Narain 14. Multivalent Glycopolymer-coated Gold NanoparticlesSarah-Jane Richards, Caroline I. Biggs, and Matthew I. Gibson  Part III: Surface Immobilized Glycopolymers 15. Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry Kai Yu, A. Louise Creagh, Charles A. Haynes, Jayachandran N. Kizhakkedathu 16. Oriented Immobilized Sialyloligo-Macroligand MicroarraySatya Nandana Narla and Xue-Long Sun 17. Glycocalyx Remodeling with Glycopolymer-based Proteoglycan MimeticsMia L. Huang, Raymond A. A. Smith, Greg W. Trieger, and Kamil Godula