The Mouse in Biomedical Research

Normative Biology, Husbandry, and Models Volume 3
2. Auflage 2006
ISBN: 978-0-12-369457-7
Verlag: Elsevier Health Sciences

Buch, Englisch, 816 Seiten, Format (B × H): 220 mm x 284 mm, Gewicht: 2127 g

Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Zielgruppe

Veterinary and medical students, senior graduate, graduate students, post-docs, and researchers who utilize animals in biomedical research

Autoren/Hrsg.

Weitere Mitwirkende

Fox, James G.

Barthold, Stephen

Davisson, Muriel

Newcomer, Christian E.

Quimby, Fred W.

Smith, Abigail

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften
• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Wirbeltiere (Vertebrata) Säugetiere (Mammalia) Primaten
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Wirbeltiere (Vertebrata) Säugetiere (Mammalia) Meeres- und Süßwassersäuger
• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Wirbeltiere (Vertebrata) Säugetiere (Mammalia) Beuteltiere (Monotremen)

Inhaltsverzeichnis

1: Gross Anatomy 2: Mouse Physiology 3: Reproductive Biology of the Laboratory Mouse 4: Endocrinology: Bone as a Target Tissue for Hormonal Regulation 5: Hematology of the Laboratory Mouse 6: Clinical Chemistry of the Laboratory Mouse

Management, Techniques, and Husbandry 7: Gnotobiotics 8: Management and Design: Breeding Facilities 9: Design and Management of Research Facilities for Mice 10: Nutrition 11: Health Delivery and Quality Assurance Programs for Mice 12: Environmental and Equipment Monitoring 13: Biomethodology and Surgical Techniques 14: In-Vivo Whole-Body Imaging of the Laboratory Mouse

Use of Mice in Biomedical Research 15: Behavioral Testing 16: Cardiovascular Disease: Mouse Models of Atherosclerosis 17: Convulsive Disorders 18: Eye Research 19: Genetic Analysis of Rodent Obesity and Diabetes 20: Mouse Models in Aging Research 21: Mouse Models of Inherited Human Neurodegenerative Disease 22: Mouse Skin Ectodermal Organs 23: Quality Control Testing of Biologics

Über Autor(innen)

Fox, James G.
Prof. Fox obtained his Master of Science degree in Medical Microbiology at Stanford University and a Doctor in Veterinary Medicine at Colorado State University, Fort Collins. Dr. Fox is an Adjunct Professor at Tufts University School of Veterinary Medicine and the University of Pennsylvania, School of Veterinary Medicine. He is a Diplomate and a past president of the American College of Laboratory Animal Medicine, past president of the Massachusetts Society of Medical Research, past chairman of AAALAC Council, and past chairman of the NCCR/NIH Comparative Medicine Study Section. He also is an elected fellow of the Infectious Disease Society of America. In 2004 Professor Fox was elected to the Institute of Medicine of the National Academy of Sciences.