Barthold / Davisson / Smith The Mouse in Biomedical Research

Normative Biology, Husbandry, and Models
2. Auflage 2006
ISBN: 978-0-08-046907-2
Verlag: Elsevier Reference Monographs
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, Band Volume 3, 816 Seiten

Reihe: American College of Laboratory Animal Medicine

Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Autoren/Hrsg.

Barthold, Stephen

Davisson, Muriel

Smith, Abigail

Inhaltsverzeichnis

1;Front Cover;1
2;The Mouse in Biomedical Research: Normative Biology, Husbandry, and Models;4
3;Copyright Page;5
4;Table of Contents;6
5;List of Reviewers;11
6;List of Contributors;12
7;Foreword;15
8;Preface;16
9;Normative Biology;16
10;Chapter 1. Gross Anatomy;18
11;Chapter 2. Mouse Physiology;40
12;Chapter 3. Reproductive Biology of the Laboratory Mouse;108
13;Chapter 4. Endocrinology: Bone as a Target Tissue for Hormonal Regulation;140
14;Chapter 5. Hematology of the Laboratory Mouse;150
15;Chapter 6. Clinical Chemistry of the Laboratory Mouse;188
16;Management, Techniques, and Husbandry;188
17;Chapter 7. Gnotobiotics;234
18;Chapter 8. Management and Design: Breeding Facilities;252
19;Chapter 9. Design and Management of Research Facilities for Mice;288
20;Chapter 10. Nutrition;338
21;Chapter 11. Health Delivery and Quality Assurance Programs for Mice;402
22;Chapter 12. Environmental and Equipment Monitoring;426
23;Chapter 13. Biomethodology and Surgical Techniques;454
24;Chapter 14. In-Vivo Whole-Body Imaging of the Laboratory Mouse;506
25;Use of Mice in Biomedical Research;506
26;Chapter 15. Behavioral Testing;530
27;Chapter 16. Cardiovascular Disease: Mouse Models of Atherosclerosis;552
28;Chapter 17. Convulsive Disorders;582
29;Chapter 18. Eye Research;612
30;Chapter 19. Genetic Analysis of Rodent Obesity and Diabetes;634
31;Chapter 20. Mouse Models in Aging Research;654
32;Chapter 21. Mouse Models of Inherited Human Neurodegenerative Disease;690
33;Chapter 22. Mouse Skin Ectodermal Organs;708
34;Chapter 23. Quality Control Testing of Biologics;748
35;Index;776
36;Color Plate Section;810