Thomas Medicinal Chemistry

An Introduction
2. Auflage 2008
ISBN: 978-0-470-51830-4
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 646 Seiten, E-Book

Medicinal Chemistry: An Introduction, Second Editionprovides a comprehensive, balanced introduction to this evolvingand multidisciplinary area of research. Building on the success ofthe First Edition, this edition has been completely revised andupdated to include the latest developments in the field.
Written in an accessible style, Medicinal Chemistry: AnIntroduction, Second Edition carefully explains fundamentalprinciples, assuming little in the way of prior knowledge. The bookfocuses on the chemical principles used for drug discovery anddesign covering physiology and biology where relevant. It openswith a broad overview of the subject with subsequent chaptersexamining topics in greater depth.
From the reviews of the First Edition:
"It contains a wealth of information in a compact form"ANGEWANDTE CHEMIE, INTERNATIONAL EDITION
"Medicinal Chemistry is certainly a text I would chose toteach from for undergraduates. It fills a unique niche in themarket place." PHYSICAL SCIENCES AND EDUCATIONAL REVIEWS

Autoren/Hrsg.

Thomas, Gareth

Inhaltsverzeichnis

Preface
Acknowledgements.
Abbreviations.
Chapter 1. An Introduction to Drugs, their Action and Discovery.
Chapter 2. Drug Structure and Solubility.
Chapter 3. Structure-activity and quantitative structures relationships.
Chapter 4. Computer aided drug design.
Chapter 5. Combinatorial Chemistry.
Chapter 6. Drugs from natural sources.
Chapter 7. Biological Membranes.
Chapter 8. Receptors and Messengers.
Chapter 9. Enzymes.
Chapter 10. Nucleic Acids.
Chapter 11. Pharmacokinetics.
Chapter 12. Drug metabolism.
Chapter 13. Complexes and chelating agents.
Chapter 14. Nitric oxide.
Chapter 15. An Introduction to drug and analogue synthesis.
Chapter 16. Drug Development and Production.
Selective further reading.
Answers to Questions.
Index.

Über Autor(innen)

Dr Gareth Thomas. The University of Portsmouth, UK