Tölgyessy / Braun / Kyrs Isotope Dilution Analysis

International Series of Monographs in Analytical Chemistry
1. Auflage 2013
ISBN: 978-1-4831-6092-4
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 194 Seiten, Web PDF

International Series of Monographs in Analytical Chemistry, Volume 49: Isotope Dilution Analysis focuses on the method of isotope dilution analysis (IDA). The book first discusses the principles, types, and theory of IDA. Classification of the methods of IDA; precision, accuracy, and sensitivity of IDA; and types of IDA are described. The text also examines experimental techniques, separation, and mass determination. The separation of components, reagents and tracers, and amount of substance separated are underscored. The text takes a look at the inorganic applications of IDA, including determination of elements and selected procedures. The text examines the applications of IDA in organic chemistry and biochemistry, particularly in the analysis of alcohols and ethers, steroids, penicillin, proteins and amino acids, and insecticides. The book discusses IDA with stable isotopes. Methods for the determination of isotopic composition, fundamentals and technique, and practical applications are underscored. The text also emphasizes the special applications of isotope dilution. Determination of the content of isotopic carriers in radioactive preparations; determination of the coefficient of self-absorption and specific activity; and determination of radioactive contaminants are discussed. The text is a vital reference for readers interested in isotope dilution analysis.

Autoren/Hrsg.

Tölgyessy, J.

Braun, T.

Kyrs, M.

Belcher, R.

Freiser, H.

Inhaltsverzeichnis

1;Front Cover;1
2;Isotope Dilution Analysis;4
3;Copyright Page;5
4;Table of Contents;6
5;Preface;10
6;Chapter 1. Principles, Types and Theory of Isotope Dilution Analysis;12
6.1;1.1. General principles;12
6.2;1.2. Classification of the methods of IDA;15
6.3;1.3. Types of IDA;18
6.4;1.4. Precision, accuracy and sensitivity of IDA;49
6.5;1.5. Advantages, drawbacks, trends;58
6.6;1.6. References;62
7;Chapter 2. Experimental Techniques, Separation and Mass Determination;70
7.1;2.1. Reagents and tracers;70
7.2;2.2. Separation of Components;77
7.3;2.3. Determination of the amount of substance separated;91
7.4;2.4. References;96
8;Chapter 3. Inorganic Applications;100
8.1;3.1. Determination of various elements;100
8.2;3.2. Selected procedures;117
8.3;3.3. References;122
9;Chapter 4. Applications in Organic Chemistry and Biochemistry;128
9.1;4.1. Alcohols and ethers;128
9.2;4.2. Carboxylic acids, acid chlorides and anhydrides;129
9.3;4.3. Sulpho derivatives;130
9.4;4.4. Proteins and amino acids;131
9.5;4.5. Steroids;138
9.6;4.6. Vitamin B12;139
9.7;4.7. Penicillin;144
9.8;4.8. Insecticides;145
9.9;4.9. Other applications in organic chemistry and biochemistry;148
9.10;4.10. References;149
10;Chapter 5. Isotope Dilution Analysis with Stable Isotopes;156
10.1;5.1. Introduction;156
10.2;5.2. Methods for the determination of isotopic composition. Analysis by mass spectrometry;157
10.3;5.3. Fundamentals and technique;159
10.4;5.4. Practical applications;161
10.5;5.5. References;168
11;Chapter 6. Special Applications of Isotope Dilution;172
11.1;6.1. Volume determination;172
11.2;6.2. Determination of solubility;178
11.3;6.3. Determination of radioactive contaminants;180
11.4;6.4. Determination of the content of isotopic carriers in radioactive preparations;182
11.5;6.5. Determination of dissociation constants;183
11.6;6.6. Studies on reaction rates and equilibria;186
11.7;6.7. Determination of the capacity of ion exchangers;187
11.8;6.8. Determination of the coefficient of self-absorption and of specific activity;189
11.9;6.9. Measurement of flow rates;190
11.10;6.10. References;191
12;Index;194