Tracey / Willsky / Takeuchi Vanadium

Chemistry, Biochemistry, Pharmacology and Practical Applications
Erscheinungsjahr 2012
ISBN: 978-1-4200-4614-4
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 250 Seiten

The first comprehensive resource on the chemistry of vanadium, Vanadium: Chemistry, Biochemistry, Pharmacology, and Practical Applications has evolved from over a quarter century of research that concentrated on delineating the aqueous coordination reactions that characterize the vanadium(V) oxidation state. The authors distill information on biological processes needed to understand vanadium effects in biological systems and make this information accessible to a wide range of readers, including chemists without extensive biological training. Building a hierarchy of complexity, the book provides a discussion of some basic principles of 51V NMR spectroscopy followed by a description of the self-condensation reactions of vanadate itself. The authors delineate reactions with simple monodentate ligands and then proceed to more complicated systems such as diols, a-hydroxy acids, amino acids, peptides, to name just a few. They revisit aspects of this sequence later, but first highlight the influence the electronic properties of ligands have on coordination and reactivity. They then compare and contrast the influences of ligands, particularly those of hydrogen peroxide and hydroxylamine, on heteroligand reactivity. The book includes coverage of vanadium-dependent haloperoxidases and model systems, vanadium in the environment, and technological applications. It also briefly covers the catalytic reactions of peroxovanadate and haloperoxidase model compounds. It contains a discussion of the vanadium haloperoxidases and the biological and biochemical activities of vanadium(V) including potential pharmacological applications. The last chapters step outside these boundaries by introducing some aspects of the future of vanadium in nanotechnology, the recyclable redox battery, and the lithium/silver vanadium oxide battery. Primary sources documented after each chapter minimize the need to search the literature, 80 illustrations provide structural information, reaction schemes, spectra, speciation diagrams, and biochemical schemes, and 22 tables present detailed information with references to primary sources. Packed with current and authoritative information, the book covers chemistry and bioinorganic vanadium chemistry in a broad and systematic manner that engenders comprehensive understanding.

Zielgruppe

Researchers in analytical and applied chemistry investigating the chemistry, biological chemistry, and pharmaceutical applications of vanadium.

Autoren/Hrsg.

Tracey, Alan S.

Willsky, Gail R.

Takeuchi, Esther S.

Fachgebiete

• Naturwissenschaften Chemie Anorganische Chemie

Inhaltsverzeichnis

s INTRODUCTION

Background VANADATE SPECIATION

Techniques

Vanadate Self-Condensation Reactions

Vanadium Atom Stoichiometry of Complexes MONODENTATE LIGANDS OF VANADATE

Alcohols and Phenols

Amines and Acids

AQUEOUS REACTIONS OF VANADATE WITH MULTIDENTATE LIGANDS

Glycols, a-Hydroxycarboxylic Acids, and Dicarboxylic Acids

Hydroxamic Acids

Thiolate-Containing Ligands

Amino Alcohols and Related Ligands

Amino Acids and Derivatives

a-Amino Acids and Peptides

Other Multidentate Ligands

COORDINATION OF VANADATE BY HYDROGEN PEROXIDE AND HYDROXYLAMINES

Hydrogen Peroxide

Hydroxylamines

Coordination Geometry of Peroxo and Hydroxamido Vanadates REACTIONS OF PEROXOVANADATES

Heteroligand Reactions of Bisperoxovanadates

Reactions of Monoperoxovanadates with Heteroligands

Oxygen Transfer Reactions of Peroxovanadates

AQUEOUS REACTIONS AND NMR SPECTROSCOPY OF HYDROXAMIDOVANADATE

Vanadium NMR Spectroscopy of Hydroxamido Complexes REACTIONS OF OLIGOVANADATES

The Smaller Oligomers

Decavanadate

INFLUENCE OF LIGAND PROPERTIES ON PRODUCT STRUCTURE AND REACTIVITY

Alkyl Alcohols

Glycols, a-Hydroxy Acids, and Oxalate

Bisperoxo and Bishydroxamido Vanadates: Heteroligand Reactivity

Phenols

Diethanolamines

Pattern of Reactivity VANADIUM IN BIOLOGICAL SYSTEMS

Distribution in the Environment

Vanadium-Ligand Complexes

Vanadium Transport and Binding Proteins

Vanadium Containing Enzymes

THE INFLUENCE OF VANADIUM COMPOUNDS ON BIOLOGICAL SYSTEMS

Vanadium Compounds on Biological Systems: Cellular Growth, Oxidation-Reduction Pathways, and Enzymes Metabolism

Pharmacological Properties of Vanadium

Mechanism of Therapeutic and Apoptotic Effects of Vanadium

Summary

Abbreviations TECHNOLOGICAL DEVELOPMENT

Molecular Networks and Nanomaterials

The Vanadium Redox Battery

The Silver Vanadium Oxide Battery

PREPARATION, CHARACTERIZATION, AND BATTERY APPLICATIONS OF SILVER VANADIUM OXIDE MATERIALS

Introduction

Preparation, Structure, and Reactivity of Silver Vanadium Oxide and Related Materials

Battery Applications of Silver Vanadium Oxide

Summary

*Each Chapter Contains References